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Ready for Launch!

TAU’s first nanosatellite ready to be launched into space.

Watch it Launch

The moment we’ve all been waiting for is now only days away: TAU’s first nanosatellite, TAU SAT1 is about to be launched into space. This exciting journey has been followed closely by many on the university’s social media, and we are happy to share that the launch itself can be watched live on Facebook on February 20 at 7:36 PM. 

 

The development of TAU-SAT1 has been followed by many on the university’s social media

 

Small Satellite – a Big Step

“This is a nanosatellite, or miniature satellite, of the ‘CubeSat’ variety,” explains Dr. Ofer Amrani, head of Tel Aviv University’s miniature satellite lab. “The satellite’s dimensions are 10 by 10 by 30 cm, the size of a shoebox. It weighs less than 2.5 kg. TAU-SAT1 is the first nanosatellite designed, built and tested independently in academia in Israel.”

 

The nanosatellite was devised, developed, assembled, and tested at the new Nanosatellite Center, an interdisciplinary endeavor of The Iby and Aladar Fleischman Faculty of Engineering,  Raymond & Beverly Sackler Faculty of Exact Sciences and the Porter School of the Environment and Earth Sciences. The entire process has taken two years – an achievement that would not have been possible without the involvement of many people: the university administration, who supported the project and the setting up of the infrastructure on campus, Prof. Yossi Rosenwaks, Dean of the Faculty of Engineering; Professors Sivan Toledo and Haim Suchowski from the Raymond & Beverly Sackler Faculty of Exact Sciences; Prof. Colin Price, researcher and lecturer in Athmospheric Sciences in the School of Geosciences and Head of the Porter School of the Environment and Earth Sciences, and, most importantly, the project team that dealt with R&D around the clock: Elad Sagi, Dolev Bashi, Tomer Nahum, Idan Finkelstein, Dr. Diana Laufer, Eitan Shlisel, Eran Levin, David Greenberg, Sharon Mishal, and Orly Blumberg.

 

Space Weather

TAU-SAT1 is a research satellite and will be conducting several experiments while in orbit. Among other things, it will measure cosmic radiation in space. “We know that that there are high-energy particles moving through space that originate from cosmic radiation,” says Dr. Meir Ariel, director of the university’s Nanosatellite Center. “Our scientific task is to monitor this radiation, and to measure the flux of these particles and their products. Space is a hostile environment, not only for humans but also for electronic systems. When these particles hit astronauts or electronic equipment in space, they can cause significant damage. The scientific information collected by our satellite will make it possible to design means of protection for astronauts and space systems. To this end, we incorporated several experiments into the satellite, which were developed by the Space Environment Department at the Soreq Nuclear Research Center.”

 

Like the weather on Earth, there is also weather in Space. This weather is linked to storms that occur on the surface of our Sun, and impact the environment around the Earth. Prof. Colin Price researches and lectures in Atmospheric Sciences and explains that “When there are storms on the Sun, highly energetic particles are fired at the Earth at speeds of hundreds of kilometers per second, and when these energetic particles hit the Earth’s atmosphere, they can cause lots of damage to satellites, spacecraft and even astronauts.” TAUSAT1 will be studying these storms and their impact on the atmosphere at the height of 400km above the Earth, testing the damage produced by the tiny particles. This will help understand the hostile environment satellite face due to space weather.

 

WATCH: TAU’s Nanosatellite Project

 

Satellite Station on Roof of Faculty Building

At an altitude of 400 km above sea level, the nanosatellite will orbit the earth at a dizzying speed of 27,600 km per hour, or 7.6 km per second. At this speed, the satellite will complete an orbit around the Earth every 90 minutes. “In order to collect data, we built a satellite station on the roof of the engineering building,” says Dr. Amrani. “Our station, which also serves as an amateur radio station, includes a number of antennas and an automated control system. When TAU-SAT1 passes ‘over’ the State of Israel, that is, within a few thousand kilometer radius from the ground station’s receiving range, the antennas will track the satellite’s orbit and a process of data transmission will occur between the satellite and the station. Such transmissions will take place about four times a day, with each one lasting less than 10 minutes. In addition to its scientific mission, the satellite will also serve as a space relay station for amateur radio communities around the world. In total, the satellite is expected to be active for several months, after which it will burn up in the atmosphere and return to the Earth as stardust.

 

TAU Joins ‘New Space’ Revolution

Launching the TAU-SAT1 nanosatellite marks TAU’s first step of joining the ‘new space’ revolution, aiming to open space up to civilians as well. The idea is that any researcher or student, from any faculty at Tel Aviv University, or outside of it, will be able to plan and launch experiments into space in the future – even without being an expert in the field.

 

Over the last few years, TAU has been working on establishing a Nanosatellite Center to build small “shoebox” size satellites for launch into space. “We are seeing a revolution in the field of civilian space”, explains Prof. Colin Price, one of the academic heads of the new center. “We call this ‘new space’, as opposed to the ‘old space’, where only giant companies with huge budgets and large teams of engineers could build satellites. 

 

After undergoing pre-flight testing at the Japanese space agency JAXA, TAU-SAT1 was sent to the United States, where it “hitched a ride” on a NASA and Northrop Grumman resupply spacecraft destined for the International Space Station. At the station, this upcoming Saturday evening, a robotic arm will release TAU-SAT1 into a low-earth orbit (LEO) around the Earth, approximately 400km above the Earth.

Last inspections in the clean room. TAU SAT1

TAU Announces First of Its Kind International Program

First in the world to combine politics, cyber and government.

Tel Aviv University launches a new program, first of its kind in the world, taught in English and targets Master’s students from Israel and overseas who wish to learn about the cyber-digital revolution and its impact on politics, society and the economy. 

Due to the coronavirus pandemic, the program was launched this year as a small-scale pilot. It is expected to expand considerably next year, to include large numbers of international students. The Program is offered by the School of Political Science, Government and International Affairs at the Faculty of Social Sciences.

Exploring the Non-Technological Sides of Cyber and Digital

The Head of the Program is Prof. Eviatar Matania, who until recently headed the Israel National Cyber Directorate. According to Prof. Matania, “The new program provides the knowledge and skills required for leading operations, strategy and policy in the rapidly developing cyber world. It is open to people with or without technological background, because it aims to understand the non-technological sides of the cyber and digital worlds: modern economics, big data, artificial intelligence, cyber threats and cyber security, and the resulting changes in society, culture and politics.”

The new program was designed with three types of students in mind: those coming from the technological disciplines who wish to understand the broader aspects of the cyber-digital revolution; those from management and government, who need these tools to manage large systems in the new world; and finally, students from various interfacing disciplines who wish to broaden their education – and anchor their own research in the dramatic changes taking place in politics, society and the economy.

Cyber – More than Cyberattacks

Prof. Matania emphasizes “When people think of Cyber, they typically think of cyberattacks. We are trying to break out of this outdated perception. Cyber is so much more than attacks and security. It is the new economy, politics, culture and society. Anyone who wishes to take part in government and the management of large systems in the future must become acquainted with the connections between strategy, policy and technology.”

TAU’s VP International, Prof. Milette Shamir, adds: “The new Cyber Program is an important addition to the series of international programs offered by TAU. Our programs are built upon a solid foundation of local expertise and include studies in security and diplomacy, conflict resolution, emergency management, environment, immigration, archaeology, documentary films and more. Today, we create programs in which Israeli and foreign students from all over the world study together, generating a unique dialogue between the local and the global.”

Featured image: “Cyber Horse” on TAU Campus

More than 20,000 participants on TAU’s Open Day 2021

Record high attendance despite event held online due to Corona.

This year, TAU wholeheartedly embraced the challenge of organizing its Open Day event online, resulting in a hugely successful event spanning over three days and comprising more than 200 Zoom meetings.

  “In the months preceding Tel Aviv University’s Open Day, we produced an introductory video of the university campus, dozens of videos about the various fields of study as well as 50 pre-recorded lectures.”, explains Alon Weinpress, Tel Aviv University’s Marketing Director. “All this, we put together in order to helped those interested in studying here gain a clear understanding of the various study programs offered here at TAU, teach them about the admission options and also give them a feel of the campus – despite the online nature of the event. Our efforts proved themselves worthwhile and the end result was very satisfactory and with few glitches. The number of participants also turned out higher than expected!”

In the Zoom meetings, potential incoming students could learn about various study programs for B.A.s and more advanced degrees, and they could also choose to take advantage of personal counselling sessions, receiving tips on how to choose a suitable field of study for oneself and more.

  More than 20,000 potential future TAU students joined the online Zoom sessions where they met and interacted with the academic and administrative staff, current students and graduates of their field of interest.

  This year saw a particularly strong interest for the fields of psychology, management, biology, chemistry, medicine, the various engineering disciplines, computer science, neuroscience, sociology, law, political science and the health professions.

  Also tremendously popular were sessions offering tips for how to choose a field of study; alternative admission routes to the regular entrance exam and how one may improve one’s chances of admission by taking online courses.

  The Open Day marked the opening of the registration season for the academic year 2021/22.   

 

Online Impact: TAU 1st in Israel, Among Top 100 Worldwide

Webometrix ranks web presence of institutions of higher education.

Tel Aviv University was ranked 73rd out of more than 31,000 institutions worldwide, number one in Israel and third in Asia by Webometrics, a ranking system designed to measure the impact of academic knowledge made available online.

The ranking is published twice a year and was created to promote the availability of academic articles online and, more broadly, open access to academic research.

Webometrics’ higher education ranking is determined by three objective factors:

  1. Impact (accounts for 50% of individual institution’s score), measured by the number of external networks linking to the institution’s webpages;
  2. Openness (10%), measured by the number of citations from top 210 authors according to Google Scholar Profiles and
  3. Excellence (40%), measured by the number of papers among the top ten percent most cited in a given field.

Hebrew University is ranked 165th (on second place in Israel) and the Technion 226th (on third place in Israel). A total of 44 Israeli institutions can be found among the top 22,504 institutions.

Read more about Webometrix ranking here >>

View the full list of Israeli institutions with ranking here >>

And the Oscar goes to…

Tel Aviv University Team Receives Prize for Significant Technological Impact to Film Industry.

The American Academy of Motion Pictures Arts and Sciences announced the Academy Award winners in the Scientific & Engineering category for 2021: Prof. Meir Feder of the Iby and Aladar Fleischman Faculty of Engineering at Tel Aviv University, and his former student and co-founding partner of the startup company Amimon, Dr. Zvi Reznic. Amimon’s senior executives Guy Dorman and Ron Yogev also share the Award. Amimon was founded in 2004 by Prof. Meir Feder, Dr. Zvi Resnic and Noam Geri (also a TAU graduate).

Watch TAU Prof. Meir Feder’s reaction to winning an Oscar:

 

 

Used in the Global Film Industry

Every year, in addition to the winners of the traditional Oscar Awards, the American Academy of Motion Pictures announces winners in various scientific and technical categories, honored for their substantial impact on the global film industry. Last night, the Academy announced that the wireless video technology developed by the Amimon team, and implemented through Amimon’s chip-set, is the winner of the prestigious Award for significant scientific and engineering contribution to the film industry.

Prof. Feder says that the prize-winning technology is now used throughout the global film industry. He explains that the technology is able to transmit very high quality video shots, reliable and without delays, from a large number of cameras, in real time, to monitors on the set. This provides the film’s director and the control crew full control of all shooting angles simultaneously.

Joseph Pitchhadze, a film creator from The Steve Tisch School of Film and Television explains that “The main importance of Prof. Meir Feder’s technological development is shortening the set building in Multi Camera productions. This novel technology saves production time and frees significantly more time for the creation itself.”

The Academy Award Committee stated: “By using novel extensions of digital data transmission and compression algorithms, and data prioritization based on error rate, the Amimon chipset supports the creation of systems with virtually unrestricted camera motion, expanding creative freedom during filming.”

Proud Moment for TAU

Prof. Feder: “This is a very exciting day for me, and a proud moment for Tel Aviv University. We developed the basic technology in 2004-2005, when everyone thought that the task was very difficult or even impossible. We knew that it was a real technological achievement, but never imagined we would win the Oscar for it. About a year ago, the Prize Committee notified us that we had been nominated, but I thought it was just a gimmick.

“About a month ago, I suddenly got an official email from the Academy in Hollywood, informing us that we had won the Oscar. We were elated. I have won many academic awards, but the Oscar is certainly the most famous, an award that every person in the street knows. For me and the great team who took part in developing the technology, this is an enormous achievement and I feel very proud.”

Featured image: The Happy Team (from left to right): Guy Dorman, Dr Zvi Reznic, Prof. Meir Feder and Ron Yogev

A Glimpse into the Wardrobes of King David and King Solomon

Archaeologists discover fabric dyed royal purple, dating back to the time of King David and King Solomon.

“King Solomon made for himself the carriage; he made it of wood from Lebanon. Its posts he made of silver, its base of gold. Its seat was upholstered with purple, its interior inlaid with love.” (Song of Songs 3:9–10) For the first time, rare evidence has been found of fabric dyed with royal purple dating from the time of King David and King Solomon.

While examining the findings from the Timna Valley dig (an ancient copper production district in southern Israel), archeologists were surprised to find remnants of woven fabric, a tassel and fibers of wool dyed with royal purple. Direct radiocarbon dating confirms that the finds date from approximately 1000 BCE, corresponding to the biblical monarchies of King David and King Solomon in Jerusalem. The rare dye is often mentioned in the Bible and appears in various Jewish and Christian contexts. This is the first time that purple-dyed textiles dating back to the Iron Age have been found in Israel, or indeed throughout the Southern Levant.

More Precious Than Gold

The research was carried out by Dr. Naama Sukenik from the Israel Antiquities Authority and Prof. Erez Ben-Yosef from the Jacob M. Alkow Department of Archaeology and Ancient Near Eastern Cultures at Tel Aviv University, in collaboration with Prof. Zohar Amar, Dr. David Iluz and Dr. Alexander Varvak from Bar-Ilan University and Dr. Orit Shamir from the Israel Antiquities Authority. The unexpected finds have been published in the prestigious PLOS ONE journal.

According to the researchers, true purple [argaman] was produced in an elaborate and difficult process from three species of mollusk indigenous to the Mediterranean Sea: The dye was produced from a gland located within the body of the mollusk by means of a complex chemical process that took several days. Today, most scholars agree that the two precious dyes, purple [argaman] and light blue, or azure [tekhelet] were produced from the purple dye mollusk under different conditions of exposure to light. When exposed to light, azure is obtained whereas without light exposure, a purple hue is obtained. These colors are often mentioned together in the ancient sources, and both have symbolic and religious significance to this day. The Temple priests, David and Solomon, and Jesus of Nazareth are all described as having worn clothing dyed purple.

 

King David wearing purple while anointed king by Samuel (Dura Europos Synagogue, Syria, 3rd century AD)

The analytical tests conducted at Bar Ilan University’s laboratories, together with dyes that were reconstructed by Prof. Zohar Amar and Dr. Naama Sukenik, identify the species used to dye the Timna textiles and the desired hues. In order to reconstruct the mollusk dyeing process, Prof. Amar travelled to Italy where he cracked thousands of mollusks (which the Italians eat) and produced raw material from their dye glands, which was then used in hundreds of attempts to reconstruct the ancient dyeing process. “This practical work took us back thousands of years,” says Prof. Amar, “and allowed us to better understand obscure historical sources associated with the precious colors of azure and purple.”

“This is a very exciting and important discovery,” explains Dr. Naama Sukenik, curator of organic finds at the Israel Antiquities Authority. “This is the first piece of textile ever found from the time of David and Solomon that is dyed with the prestigious purple dye. In antiquity, purple attire was associated with the nobility, with priests, and of course with royalty. The gorgeous shade of the purple, the fact that it does not fade, and the difficulty in producing the dye, all made it the most highly valued of the dyes, which often cost more than gold. Until the current discovery, we had only encountered mollusk-shell waste and potsherds with patches of dye, which provided evidence of the purple industry in the Iron Age. Now, for the first time, we have direct evidence of the dyed fabrics themselves, preserved for some 3000 years”.

Silicon Valley of the Iron Age

Prof. Ben-Yosef says, “Our archaeological expedition has been excavating continuously at Timna since 2013. The region’s extremely dry climate enables us to recover organic materials such as textile, cords and leather from the Iron Age, from the time of David and Solomon, providing us with a unique glimpse into life in biblical times. We can excavate for another hundred years in Jerusalem and still, we will not be able to discover textiles from 3000 years ago. The state of preservation at Timna is exceptional and it is paralleled only by much more recent sites, such as Masada and the Judean Desert Caves.”

“In recent years, we have been excavating a new site inside Timna known as ‘Slaves’ Hill’. The name may be misleading, since far from being slaves, the laborers were highly skilled metalworkers. Timna was a production center for copper, the Iron Age equivalent of modern-day oil. Copper smelting required advanced metallurgical understanding that was a guarded secret, and those who held this knowledge were the ‘Hi-Tech’ experts of the time. Slaves’ Hill is the largest copper-smelting site in the valley and it is filled with piles of industrial waste such as slag from the smelting furnaces. One of these heaps yielded three scraps of colored cloth. The color immediately attracted our attention, but we struggled to believe that we had found true purple from such an ancient period”.

Royal Argaman – the Most Prestigious Color

The dye was identified with an advanced analytical instrument (HPLC) that indicated the presence of unique dye molecules, originating only in certain species of mollusk. According to Dr. Naama Sukenik, “Most of the colored textiles found at Timna, and in archaeological research in general, were dyed using various plant-based dyes that were readily available and easier to dye with. The use of animal-based dyes is regarded as much more prestigious, and served as an important indicator of the wearer’s high economic and social status. The remnants of the purple-dyed cloth that we found are not only the most ancient in Israel, but in the Southern Levant in general. We also believe that we have succeeded in identifying the double-dyeing method in one of the fragments, in which two species of mollusk were used in a sophisticated way, to enrich the dye. This technology is described by the Roman historian Pliny the Elder, from the first century CE, and the dye it produced was considered the most prestigious.”

Prof. Ben-Yosef identifies the copper-production center at Timna as part of the biblical Kingdom of Edom, which bordered the Kingdom of Israel to the south. According to him, the important finds should revolutionize our concepts of nomadic societies in the Iron Age: “The new finds reinforce our assumption that there was an elite at Timna, attesting to a stratified society. In addition, since the mollusks are indigenous to the Mediterranean, this society obviously maintained trade relations with other peoples who lived on the coastal plain. However, we do not have evidence of any permanent settlements in the Edomite territory. The Edomite Kingdom was a kingdom of nomads in the early Iron Age.”

“When we think of nomads, it is difficult for us to free ourselves from comparisons with contemporary Bedouins, and we therefore find it hard to imagine kings without magnificent stone palaces and walled cities. Yet, in certain circumstances, nomads can also create a complex socio-political structure, one that the biblical writers could identify as a kingdom. Of course, this whole debate has repercussions for our understanding of Jerusalem in the same period. We know that the Tribes of Israel were originally nomadic and that the process of settlement was gradual and prolonged. Archaeologists are looking for King David’s palace. However, perhaps King David did not express his wealth in splendid buildings, but rather with objects more suited to a nomadic heritage such as textiles and artifacts.”

According to Prof. Ben-Yosef, “It is wrong to assume that if no grand buildings and fortresses are found, then biblical descriptions of the United Monarchy in Jerusalem must be literary fiction. Our new research at Timna has showed us that even without such buildings, there were kings in our region who ruled over complex societies, formed alliances and trade relations, and waged war on each other. The wealth of a nomadic society was not measured in palaces and monuments made of stone, but in things that were no less valued in the ancient world – such as the copper produced at Timna and the purple dye that was traded with its copper smelters.”

Featured image: Wool textile fragment decorated by threads dyed with Royal Purple, ~1000 BCE, Timna Valley, Israel. Photo: Dafna Gazit, courtesy of the Israel Antiquities Authority

Increased Diversity Secured On TAU Campus

Marketing efforts and direct lines of communication generate impressive results.

Consistent and Targeted Marketing

The number of Arab students in technological studies Electrical Engineering and Computer Science have doubled over the past five years: 459 Arab students (150 of these women) studied technology professions at TAU in 2020 studied technology professions at TAU in 2020, compared to 237 (59 of these women) in 2016. 

This significant achievement is not the result of affirmative action or easing of admission conditions, but of consistent and targeted marketing carried out over several years. The target audience in this case was Arab high school students and the goal was to increase the number of Arab students of hi-tech disciplines to reflect the proportionate size of the Arab population in Israel.

In 2020, 307 Arab students (18% of Electrical Engineering students, equal to the percentage of Arabs in Israeli society) attended TAU’s School of Electrical Engineering, compared to 136 (about 9% of Electrical Engineering students) students in 2016. There were 97 women (approx. 6%) studying Electrical Engineering in 2020, a significant increase from 31 (2.1%) in 2016.

TAU’s Blavatnik School of Computer Science, experienced a 50% growth in the number of Arab bachelor students. In 2020, 152 Arab students (12.2%, 53 of these women (4.3%)) studied for a bachelor’s degree in computer science, compared to 101 students (8.7%, 28 of these women (2.4%)) in 2016. 

Reaching out to Minorities

Alon Weinpress, Tel Aviv University’s Marketing Director, says: “In recent years we have made great efforts to convey to those from the Arab society interested in studying that Tel Aviv University is a home for them. Our efforts include: visiting high schools; organizing tours of the TAU campus; participating in fairs; sponsoring major events such as hackathons dedicated to Arab society and more. I am thrilled that these efforts are bearing fruit in general, and in the fields of engineering and computer science in particular.”

“In addition to increasing the number of Arab students at the university, we also wish to diversify enrollment and expose candidates to potential and important fields of study,” adds Shady Othmany, Marketing Coordinator for the Arab Society within the university’s Strategic Planning and Marketing Division. 

“Increasing the number of Arab students in high-tech professions has been challenging and the admission requirements are high. Despite this, and thanks to our chosen work method and strategies and the support of our professional marketing team and the assistance of Dr. Youssef Mashharawi, we have gradually advanced towards our goal.”

“The secret behind our success can be explained by our decision to be part of Arab society. We have consistently been conducting activities aimed at the Arab sector, in collaboration with multiple associations and institutions. We prioritize meeting the different needs of those interested on a personal level, also during the pandemic.”

“The father of a candidate contacted me directly when he understood the date for the entrance test was postponed because of Corona. He was concerned about his son’s chances to get accepted to our Electrical Engineering studies. We offered an alternative admission route for his son. This option had been advertised on the university website, but being able to make a simple phone call and have a pleasant conversation in their own language, lowered the stress levels for the father and son. Being able to offer this type of assistance is immensely satisfying for me.” concludes Shady.

 

Shady Othmany in dialogue with a group of university candidates

Prof. Mark Shtaif, TAU Rector notes that: “Along with academic excellence, Tel Aviv University sees great importance in making higher education accessible to various sectors of the population, with particular emphasis on the Arab society. A few years ago, we set an ambitious goal for ourselves: to increase the proportion of Arab students in our high-tech studies to reflect the proportion of Arabs in the Israeli population. I am pleased to see that in Electrical Engineering we managed to reach our goal even sooner than expected, and hope the positive trend that we are witnessing in Computer Science will continue as well, until we attain our goal.”

Featured image: Shady Othmany, Marketing Coordinator for the Arab Society, with Arab students at the Tel Aviv University campus

Tel Aviv’s Ecological Oasis: The Yehuda Naftali Botanic Garden at TAU

A donor-supported renovation focuses on research, facilities and visitor access.

By Lindsey Zemler

TAU’s Yehuda  ​Naftali Botanic Garden is a Tel Aviv oasis for all, a collaborative research hub for plant scientists, engineers and neuroscientists, as well as a beautiful urban nature site that welcomes schoolchildren, soldiers and the general public and numbers among the city’s top tourist attractions.

In the last few months, the Garden has been undergoing a massive rejuvenation and enhancement program.

“Thanks to the generous support of Mr. Yehuda Naftali, this long-awaited renovation marks a significant step forward in our mission to be at the cutting edge of botanical research, education and conservation in Israel,” says Prof. Abdussalam Azem, Dean of the George S. Wise Faculty of Life Sciences, to which the Garden belongs. “This project brings us to the next level in improving infrastructure and access.”

Path construction in progress. Photo: Rafael Ben-Menashe.

A priority in planning the renovations, which are almost complete, was to increase access to all corners of the 34-dunam (8-acre) site, including to school groups, families, researchers, and students. This involved making the paths easier to navigate with wheelchairs, strollers, or groups.

Upon entering, the visitor will enjoy seeing native flora in the new beds adjacent to the garden’s western boundary fence, which are placed according to where they are found in Israel, from north to south.  The acacia tree planted by Mr. Naftali at the Garden’s inauguration in 2019 can be found there, growing nicely.

A variety of paths throughout the Garden. (Left): A natural blanket of pine needles is reminiscent of a walk through the Carmel Forest. Photos: Rafael Ben-Menashe.

The main pathways are wide, paved and comfortable for walking in groups. Smaller paths branch out among various habitats to allow visitors an immersive nature experience. They are all designed to emulate natural processes; sometimes a section is left unpaved for water flow.

Water pond with newly added wooden deck. Photo: Moshe Bedarshi.

Rainfall naturally flows downhill and arches in a waterfall to fill a pond, where the addition of wooden decks allows the visitor to stand comfortably at the edge of the water to view wetland plant species.

“When we planned the renovations, we put a lot of thought into the best visitor experience: to create a feeling of being transported to a nature reserve and being able to experience it from close range,” explained Kineret Manevich, Public Outreach Coordinator of the Garden.

New irrigation control center (left) and irrigation pipe (right) in the pine forest habitat. Photos (left) by Rafael Ben-Menashe and (right) by Moshe Bedarshi.

A new computer-controlled irrigation system is part of the critical infrastructure changes in the renovation plan. A large, complex network of pipes provides thousands of plants with essential water.

(Left): Rare plants being cared for in the nursery and (right) image of geo-mapping software. Photo (left) by Rafael Ben-Menashe and (right) courtesy of the Botanic Garden.

The Garden is also an active research center, where every plant is mapped and monitored, creating a robust database of botanical research. In addition, rare plants are rehabilitated and returned to nature.

The Garden offers a complete sensory experience, full of texture, color and shapes.

The area is a living ecosystem providing refuge to plants, animals, and of course, humans seeking nature without leaving Tel Aviv. The Yehuda Naftali Botanic Garden will be open to the public, and together with the adjacent Steinhardt Museum of Natural History will welcome visitors of all kinds.

Cancer Breakthrough: Cells’ Uniqueness is Also Weakness

TAU research proves connection for first time, can be base for cancer drugs.

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers since the mid-19th century. The search for unique characteristics of cancer cells is a building block of modern cancer research. A new study led by researchers from Tel Aviv University shows, for the first time, how an abnormal number of chromosomes (aneuploidy) — a unique characteristic of cancer cells that researchers have known about for decades — could become a weak point for these cells. The study could lead, in the future, to the development of drugs that will use this vulnerability to eliminate the cancer cells.

The study, which was published in Nature, was conducted in the laboratory of Dr. Uri Ben-David of the Sackler Faculty of Medicine at Tel Aviv University, in collaboration with six laboratories from four other countries (the United States, Germany, the Netherlands, and Italy).

Aneuploidy is a hallmark of cancer. While normal human cells contain two sets of 23 chromosomes each — one from the father and one from the mother — aneuploid cells have a different number of chromosomes. When aneuploidy appears in cancer cells, not only do the cells “tolerate” it, but it can even advance the progression of the disease. The relationship between aneuploidy and cancer was discovered over a century ago, long before it was known that cancer was a genetic disease (and even before the discovery of DNA as hereditary material).

According to Dr. Ben-David, aneuploidy is actually the most common genetic change in cancer. Approximately 90% of solid tumors, such as breast cancer and colon cancer, and 75% of blood cancers, are aneuploid. However, our understanding of the manner in which aneuploidy contributes to the development and spread of cancer is limited.

In the study, the researchers used advanced bioinformatic methods to quantify aneuploidy in approximately 1,000 cancer cell cultures. Then, they compared the genetic dependency and drug sensitivity of cells with a high level of aneuploidy to those of cells with a low level of aneuploidy. They found that aneuploid cancer cells demonstrate increased sensitivity to inhibition of the mitotic checkpoint – a cellular checkpoint that ensures the proper separation of chromosomes during cell division.

They also discovered the molecular basis for the increased sensitivity of aneuploid cancer cells. Using genomic and microscopic methods, the researchers tracked the separation of chromosomes in cells that had been treated with a substance that is known to inhibit the mitotic checkpoint. They found that when the mitotic checkpoint is perturbed in cells with the proper number of chromosomes, cell division stops. As a result, the chromosomes in the cells separate successfully, and relatively few chromosomal problems are created. But when this mechanism is perturbed in aneuploid cells, cell division continues, resulting in the creation of many chromosomal changes that compromise the cells’ ability to divide, and even cause their death.

The study has important implications for the drug discovery process in personalized cancer medicine. Drugs that delay the separation of chromosomes are undergoing clinical trials, but it is not known which patients will respond to them and which will not. The results of this study suggest that it will be possible to use aneuploidy as a biological marker, based on possibility to find the patients who will respond better to these drugs. To put it another way, it will be possible to adapt drugs that are already in clinical trials for use against tumors with specific genetic characteristics.

In addition, the researchers propose focusing the development of new drugs on specific components of the mechanism of chromosomal separation, which were identified as especially critical to aneuploid cancer cells. The mitotic checkpoint is made up of several proteins. The study shows that the aneuploid cells’ sensitivity to inhibition of the various proteins is not identical, and that some proteins are more essential to cancer cells than others. Therefore, the study provides motivation for developing specific drugs against additional proteins in the mitotic checkpoint.

“It should be emphasized that the study was done on cells in culture and not on actual tumors, and in order to translate it to treatment of cancer patients, many more follow-up studies must be conducted. If they hold true in patients, however, our findings would have a number of important medical implications,” Dr. Ben-David says.

The study was conducted in collaboration with laboratories from five countries: Dr. Zuzana Storchová, (Technische Universität Kaiserslautern, Germany), Dr. Jason Stumpff (University of Vermont, USA), Dr. Stefano Santaguida (University of Milano, Italy), Dr. Floris Foijer (University of Groningen, the Netherlands), and Dr. Todd Golub (The Broad Institute of MIT and Harvard, USA).

TAU Excavation Examines “Ancient High Tech”

Plant remains elucidate early Israel’s role in global metals industry.

By Melanie Takefman

The wind is the first to “welcome” visitors to the hilltop TAU excavation at Yotvata, a kibbutz in the Arava desert. It lashes out at anyone or anything in its path, merciless. The steep ascent to the site is no more hospitable.

“This site is here precisely for this reason,” explains Mark Cavanagh, a doctoral candidate at TAU’s Chaim Rosenberg School of Jewish Studies and Archaeology. “The winds powered the smelting furnaces—fanned the flames—in the early periods of the copper industry.” The dig at Yotvata is part of TAU’s Central Timna Valley Excavation, led by Prof. Erez Ben-Yosef. Since 2012, Ben-Yosef and his team have studied the ancient mining industry in Israel’s South, which peaked around 1,000 BCE, during the time of Biblical kings David and Solomon. During the current dig season, the Timna Valley team is studying the earlier stages, in the third millennium BCE, of what Ben-Yosef refers to as the “high tech of the ancient world.”

The wind is the first to “welcome” visitors. TAU excavation at Yotvata

“We’re interested in how the metallurgical industry started,” says Ben-Yosef. His team has found evidence that the early mines’ products served the Egyptian empire. “The elite needed luxury materials such as jewelry, tools and ornaments… copper was part of the social processes that made civilizations and empires.”

According to his hypothesis, the communities surrounding Timna were much more important than previously thought because they had ties to the “great Egypt of the pyramids,” Ben-Yosef says. Moreover, their prominence points to the crucial role of the metal’s industry in the emergence of the Egyptian empire as well as the first urban societies, which developed at around that time in northern and central Israel.

Cavanagh, a New Jersey native, is an archaeobotanist, studying plant remains to learn about the past. He completed an International MA in Archaeology at TAU and is now in the second year of his PhD at TAU, under the supervision of Ben-Yosef and Dr. Dafna Langgut.

At Timna, Cavanagh seeks vestiges of the fuel sources that fed the copper smelting furnaces. By analyzing them, he gleans insights into the broader context of the mines and the role they played in the third millennium BCE. For example, the types of plant remains he finds can tell him about that period’s ecology and climate. Through traces of pollen, for example, he hopes to learn if the area was more savannah-like 5,000 years ago.

One of the season’s exciting finds was a grave attributed to the Early Bronze Age at Yotvata. Through it, Cavanagh hopes to learn more about the inhabitants of the mining site. “The entire area is covered in graves.” Together, they create a path that indicates travel routes. “We’ll begin to understand the tracks that people were taking in the Early Bronze Age,” he says, both in terms of trade and migration.

Each of these elements, pieced together, will shed light onto what Cavanagh calls “one of the greatest stories of human history: How and when and why did people learn to turn pretty rocks into useful metal?“

Stay tuned for the next season!

Featured image: hilltop TAU excavation at Yotvata

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