Tag: Covid-19

Our COVID-19 researchers weigh in on the latest strain.

As scientists race to understand the newest Omicron variant of COVID-19, Tel Aviv University experts share insights—largely reassuring—on the situation. The latest coronavirus strain dominating headlines was first discovered in South Africa in November. Cases have since emerged around the globe, including in Israel. Under the auspices of TAU’s Center for Combating Pandemics, dozens of teams across campus are contributing to global efforts to understand and combat the pandemic. Here is what they are saying about Omicron:  

“Keep Calm and Carry On”— with Protection 

Amid the media maelstrom and uncertainty surrounding Omicron, Dr. Oren Kobiler of the Sackler Faculty of Medicine proscribes the popular adage “keep calm and carry on.” 

“It is best not to panic over Omicron,” he says.​ “This new variant will not change the entire dynamic of the disease. Vaccine efficacy against severe illness was maintained against all variants so far, and it is unlikely that their efficacy will decrease against this variant.” ​

​From a biological and virological perspective, he notes that the Omicron variant is unique and needs further examination. However, the best thing for the general public to do is get fully vaccinated and wear masks. 

“The worst-case scenario is that we will face another wave of infection, but that should not lead to higher rates of mortality due to current vaccination rates,” he says.  

Kobiler, a virology expert, says that Israel is among countries with the highest rates of COVID-19 booster vaccination among its population. “Several immunological studies indicated that this gives us an edge for fighting new variants.” 

“Until everyone is vaccinated, though, we will keep seeing more mutations and variants,” he stresses, adding that widespread inoculation is particularly critical in developing countries where infection and mortality rates are significantly higher than in wealthier nations.  

Get Booster Shots ASAP 

  Prof. Eran Bacharach

The emergence of the Omicron variant has raised questions about the efficacy of booster shots in their current form as opposed to revamped inoculations that may emerge in the future.

Prof. Eran Bacharach, of the Wise Faculty of Life Sciences and a member of the Israeli Ministry of Health’s COVID-19 Vaccine Advisory Team, implores the public to get third injections as soon as possible of COVID-19 vaccines rather than waiting for new versions that may be better formulated to target Omicron. 

“It will still take at least several months before new versions of COVID-19 vaccines are available on the market,” says Bacharach, the head of the molecular virology lab at the Shmunis School of Biomedicine and Cancer Research.  

Prof. Adi Stern, also of the Shmunis School, echoes Kobiler and Bacharach’s calls, adding that until there are updated vaccines, additional new variants will likely emerge. She explains that the spread of infection within a population—or “chain of infection”—is what enables the development of mutations and variants.  

“Inoculation, even with vaccines that aren’t specifically formulated to target a certain strain, is the only thing that will break these ‘chains of infection’ and prevent the emergence of new variants,” says Stern, whose lab has been studying the evolution of SARS-CoV-2, now including the origin and behavior of the Omicron variant.  

Prof. Adi Stern

Furthermore, she notes that current vaccines are based on the original wild-type strains seen early in the pandemic. “These vaccines have proved effective thus far in protecting against severe disease and death from existing variants, including the Delta strain. Considering all this, it’s much better to be vaccinated now to promote individual and herd immunity.” 

Minding the Balance 

Between “pandemic fatigue” and hyperbolized fears stoked by some officials, the latest variant outbreak renews questions about how to manage the situation. To avoid spurring panic, Dr. Bruria Adini cautions that public officials should not jump to conclusions about the severity of the Omicron variant when addressing the public. 

“The public needs to be a full partner in the pandemic response. If officials lose the public’s trust, the situation will deteriorate,” says Adini, head of the Department of Emergency and Disaster Management in the School of Public Health, Sackler Faculty of Medicine. 

Dr. Bruria Adini

Adini, who has been conducting long-term studies of COVID-19 since March 2020, surveys the public every few months to gauge their emotional status and level of resilience over time. Her research continuously incorporates new developments that contribute to public perceptions, such as the risk versus reward of vaccinating children.  

“It could be Omicron today or a new variant tomorrow, but we’ll live with COVID-19 for at least the near future,” she says.

One of the main concerns countries need to manage now is the prevention of healthcare system overloads.”Strengthening the capacity of medical systems with measures such as more ICU and internal medicine beds will foster more public resilience, which my research has found to be the greatest predictor of behavior such as agreeing to get vaccinated,” she says.  

As opposed to earlier in the pandemic, she notes that the public and governments have shifted their mindset toward coronavirus. She points to the lessening of widespread lockdowns and closures of workplaces and schools amid each new development as a positive indication of evolving pandemic responses.  

Select Omicron media coverage featuring TAU experts:  

• Prof. Jonathan Gershoni & Dr. Oren Kobiler: What is the new COVID Omicron variant? Here’s what we know (The Jerusalem Post)
• Prof. Jonathan Gershoni: Israel on High Alert over Omicron Variant (i24 News)
• Dr. Oren Kobiler: Biggest Change Since COVID Started’: What’s Omicron and How to Beat It, per This Israeli Expert (Haaretz)
• Dr. Oren Kobiler: Israel bans arrivals from Africa over omicron variant (i24 News)
• Prof. Adi Stern: ‘Overwhelming’: Israeli virus sleuth researchers work flat-out on Omicron puzzle (The Times of Israel)

TAU researchers contribute a new piece to the puzzle on the effectiveness of COVID-19 vaccination.

TAU’s Dr. Bruria Adini spoke to TAU Review about mental health, resilience and hope in the post-Corona world.

By Melanie Takefman Dr. Bruria Adina, head of the Emergency and Disaster Management Program at TAU’s School of Public Health, Sackler Faculty of Medicine, and TAU’s Center for Combating Pandemics, has been measuring Israelis’ resilience for years, both during “routine times” and crises. When COVID-19 broke in March 2020, Adini and her team surveyed a sample group of Israelis regarding their mental well-being. They continued to do so every 2-3 months to evaluate their levels of distress, depression and anxiety as well as individual, community and national resilience.

How has COVID-19 affected Israelis’ mental health?

It affected them in almost every facet of their lives. Until October 2020, the rates of distress rose significantly—both anxiety and depression. We got to the point where one in five people had high levels of depression, and one in three had high levels of anxiety. All three levels of resilience—individual, community and national—dropped through much of the first year of COVID-19. Then, in January 2021, we saw a small increase in community and national resilience, most probably a result of the vaccination campaign. We can explain this by the fact that the vaccination campaign offered hope that things will get better. People felt that the country was standing by their side. The authorities were doing something. At the same time, there was a substantial decrease in individual resilience. People didn’t feel the vaccination campaign was impacting their lives yet. They were still stuck at home. They didn’t know what was going to happen with their children’s education. They were still experiencing economic instability.  

How has resilience varied with age?

We expected to see the highest threat and the lowest resilience among the elderly population, because we heard that they were the most at risk and COVID-19 could be lethal for them. But what we found was the opposite. It was the younger populations, aged 31-40, who showed the lowest level of resilience and the highest levels of stress, anxiety and perceived threat. The younger people felt the most impact economically because they are the backbone of the workforce, while those who live on pensions were less affected. This younger group also worried about the impact of the pandemic on their children, as the school system was closed. In addition, we found that the resilience of university and college students was lower than that of the average population. Their distress and anxiety levels were higher, as was a perceived threat to their academic success. In addition, many of them lost jobs in the industries that were shut down during the pandemic, such as restaurants and bars.

How can governments help people be more resilient during a pandemic?

Transparency is key to the management of any emergency. Having a clear and unified message is also important. If you enable open dialogue, authorities can provide information that the public needs in a way that builds trust. In other words, the government needs to make the public part of the solution, to make them a partner and to empower them. For example, the government and other bodies can invite the public to relay what is happening on the ground. In this way, citizens can have an impact on policy and crisis response. On the flipside, we saw that messaging that inspired fear among the populace worked only for a short time. Also, the threat of cash fines didn’t convince people to follow the guidelines, such as wearing masks. What does have an impact is helping people understand how their behavior will impact those they care about—their community, family members and so on. During the pandemic, we also saw fruitful connections between academia and decision-makers. We provided data and evidence of what the public feels, which they could take into consideration in determining policy. We collaborated with the Ministries of Health, Social Equality and Welfare.

Some people think that the next pandemic will be a mental health pandemic. Do you agree with this statement?

If you’re asking me is this pandemic going to have long-term mental health repercussions, the answer is certainly yes. No type of adversity or pandemic is singular. The health risk caused economic instability. The economic instability created political instability. Mental health impacts your ability to function, your ability to function impacts your economic situation, your economic situation impacts your mental health, your self-confidence, your certainty of what the future holds, and so on. So it’s not only about mental health; it affects our economy and society as well.

What are the main lessons that COVID-19 has taught us?

Even when we need to make drastic changes in our lives, we have the power to overcome and continue to function. For example, the education system closed and distance learning was a severe blow but in academia, for example, we didn’t miss one day of teaching. We switched to Zoom, and that’s going to impact online learning in the years to come. We saw the same concerning the economy. People worked from home. I think the pandemic led to some positive insights, and these are becoming clearer as time passes. We’re going to see that our society can make the necessary modifications to improve our way of life. That’s the exact definition of resilience: To adapt to what is happening and still try to bounce forward. Featured image: Dr. Bruria Adina, head of TAU’s Emergency and Disaster Management Program