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Tag: Life Sciences

Inventive Study to Develop Biological Solutions for Agriculture

TAU and ag-biotech company PlantArcBio to collaborate on development of RNAi-based products.

Genetically improved plants can be a real-life magic stick for solving global famine issues. In a first-of-its-kind study, Ramot, the Technology Transfer Company of Tel Aviv University will cooperate with ag-biotech company PlantArcBio to develop innovative RNAi-based biological solutions for agriculture.

RNAi technology enables a temporary external disruption of RNA (ribonucleic acid) molecules, diminishing the amount of Messenger RNA (mRNA), thus temporarily reducing the expression of specific genes, without modifying or genetically engineering the organism’s DNA. Externally applied RNAi molecules affect specific genes for a specific time period, as required for positive effects like crop protection and yield enhancement. 

Specifically, the research will focus on testing the joint technology’s contribution to the stability of RNAi-based products and their ability to penetrate plants and insects.

Joining Forces

The first-of-its-kind joint study will examine the efficacy of PlantArcBio‘s RNAi technology for agriculture, combined with the unique lipid-based RNA delivery technology developed by Prof. Dan Peer, TAU’s Vice President for R&D, head of the Center for Translational Medicine and a member of both the Shmunis School of Biomedicine and Cancer ResearchGeorge S. Wise Faculty of Life Sciences, and the Center for Nanoscience and Nanotechnology, and a pioneer using RNA to manipulate cells in cancer and other immune related diseases.  

 

Prof. Dan Peer

“We see great value in contributing to the development of RNAi-based products addressing global issues and providing an ecological and environmentally friendly solution to the global challenges of sustainability in agriculture and food security,” says Peer.

Keren Primor Cohen, CEO of Ramot, believes there is “extensive commercial potential for this combined technology” and welcomes the collaboration with PlantArcBio.

The research will be carried out both at PlantArcBio‘s Laboratories and at Prof. Dan Peer’s Laboratory of Precision NanoMedicine at Tel Aviv University. According to Dror Shalitin, Founder and CEO of PlantArcBio, the results are expected within approximately 12 months.

Reading Tea Leaves

What is the origin of tea, and does the climate crisis threaten its production?

Tea – the ancient beverage comes in different flavors and colors. The Queen of England will never go without her afternoon tea, in India it’s enjoyed with milk and spices and we all like to pour ourselves an occasional cup of Earl Grey, especially when winter comes knocking. But have you ever wondered whether the saying “all the tea in China” really does indicate where tea drinking started? Or if the soothing drink may be affected by the climate crisis? Should we, in fact, be drinking it? We have, and our researchers explained, surprised us and busted some myths in the process.

When the Chinese Mystics Met the Tea Plant

We’re not going to keep you in suspense: It turns out that the coveted drink was sipped by the Indian Buddhist monks two thousand years ago – long before it became an integral part of Chinese culture and a long, long time before it became popular in Western cultures.

“The tea plant was known in China as early as the first centuries BCE, but recent studies show that the custom of drinking tea was brought to China from India,” explains Prof. Meir Shahar from The Department of East Asian Studies of The Lester and Sally Entin Faculty of Humanities at Tel Aviv University, who researches, among other things, the influence of Indian culture on Chinese religion and literature.

“In the first centuries CE Buddhism came to China from India and the Buddhist monks, who wanted to stay awake during the meditation, used to drink tea. The Chinese monks would observe this, and went on to adopt the custom as well, which then continued to spread to the rest of the Chinese population.”

While tea originates from India, the origin of the word ‘tea’ in most of the world’s languages, however, is Chinese. “In northern China it is called cha, hence the Russian chai, and in southern China it is pronounced as tcha, which is the origin of the English word tea,” reveals Prof. Shahar.

Buddhist monks on their tea break

What’s in Your Cuppa?

Buddhist monks realized long ago that tea keeps them awake and today, thanks to science, we are able to explain how the active ingredients of the plant affect us.

“Contrary to many people’s beliefs, all types of tea are produced from the same plant, namely the leaves and buds of the Camellia Sinensis plant. While there are several varieties of the plant, the types of tea that we are familiar with – white, green, oolong and black – differ according to the part of the plant from which they are produced and the way they’re processed. Green tea, for example, contains less caffeine than black tea. The leaves used to produce green tea undergo a minimal drying process while the leaves intended for black tea undergo drying and fermentation,” explains Guy Shalmon, a sports nutritionist and exercise physiologist at the Sylvan Adams Sports Institute.

“Tea leaves contain substances known as flavonoids. Their composition, however, varies from one tea to another. For example, green tea has a higher concentration of a substance called epigallocatechin 3-gallate, known for short as ‘EGCG’, than black tea which undergoes a prolonged processing process. It has antioxidant activity and is attributed various health effects,” says Guy.

“Having said that, tea may reduce the absorption of iron-derived iron minerals. The polyphenols (compounds with antioxidant properties), which exist in tea leaves, may bind inorganic iron mineral before it is excreted in the feces. In order to prevent this, one does not need to give up drinking tea, but instead make sure not to drink it while consuming iron-rich plant foods,” he advises.

Will Tea Survive the Climate Crisis?

The climate crisis brings with it many changes and different regions of the world are experiencing major climate fluctuations, ranging from heat and droughts to floods, storms and extreme cold. This could threaten the continued survival of agricultural crops. Some plants have crossed oceans and been absorbed by other continents, but what about those that require special conditions to thrive? Will the tea plant survive the changing conditions?

“A plant can adapt to new conditions up to a certain limit,” says Prof. Shaul Yalovsky of the School of Plant Sciences and Food Security at The George S. Wise Faculty of Life Sciences, who studies plant development mechanisms and their response to environmental stresses. His lab has succeeded in developing tomato varieties that consume less water and still deliver the same amounts of fruit while maintaining its quality.

“Tea is a crop that grows in very rainy areas. Therefore, it is not cultivated in an area like Israel, for example. Tea plantations are usually located on hills, where the weather is humid and cool to the appropriate extent and the soil is deep enough.”

The tea fields stretching over hills and mountains. Tea harvest in action


Disguised as Tea

Did you know that red “tea” (also known as “red bush tea”) is actually an infusion from the Rooibos plant that grows in South Africa? Because it is processed in the same way as the tea plant, it is commonly referred to as “red tea”, while in reality it is not a tea, but an herbal infusion. It is naturally caffeine-free.


Just like many other plants, tea requires specific conditions to grow: deep and airy soil rich in minerals, and an optimal temperature range between 18 and 20 degrees Celsius. “Tea is sensitive to cold, dryness, humidity and lighting conditions. For example, high humidity impairs the quality of the tea while periods of dryness increase its quality, and growing at high altitudes increases the quality of the tea but lowers the amount of crop,” explains Prof. Yalovsky.

The tea is grown in Asia, Africa and South America. The six largest tea producers in the world are China, India, Kenya, Sri Lanka, Vietnam and Turkey. So what happens if growing conditions in East and Southeast Asia change? Prof. Yalovsky explains that it is necessary to adapt the types of tea plants according to their growing areas. “What works at one location does not necessarily work elsewhere: what grows well in East and Southeast Asia will not necessarily grow well in Kenya or Turkey, for example. Even if we should manage to copy a crop from one place to another, we may not succeed in maintaining its qualities and taste.”

When we drink Earl Grey tea we expect a very specific taste, and if the same tree were to be grown elsewhere – where the temperature may be the same as the original habitat but the soil is not – we would likely notice a change in the taste of the product. This is possibly one of the reasons why drinking Japanese green tea differs in taste from Chinese green tea.

With regard to the future of the in-demand beverage, Prof. Yalovsky says: “Even if the regions of the cultivated areas should experience floods – the tea plantations are positioned on the slopes of hills and mountains so it should not become an issue.” Another good news is that unlike many crops that depend on pollination to develop fruit – the tea plant is less reliant on this. “In the production of tea, we use its leaves and not its flowers or fruits and so it can be propagated by pruning (cutting a branch from a mature plant, a so-called ‘mother plant’, and creating a new plant through rooting). This method also ensures the genetic uniformity of the ‘daughter plants’, with everything that implies,” he concludes.

We made sure to ask Guy Shalmon which type of tea (if any) he recommends that our students drink during the exam period, to which he replied: “Actually, I wouldn’t say there’s any unique advantage or need to drink tea during an exam period. I’d say drink the kind of tea that you fancy and, ideally, try to rotate different types of tea. If the need for caffeine is the main consideration, black tea is the best choice, as it has the highest caffeine concentration. Black tea contains approx. 60-40 mg of caffeine per cup, while green tea contains only 20-15 mg.”

Well, who needs the exams as an excuse, anyway? If you’re like us, we suggest you pour yourself a cuppa on any day of the week – no special occasion required – and enjoy a peaceful break from everything and everyone.

New Ethical Code for World Research of Ancient DNA

TAU researcher was part of international team of experts who composed ethical standard.

For the first time, an international team of experts, among them TAU anthropologist and paleo-geneticist Dr. Viviane Slon from the Sackler Faculty of Medicine and the Dan David Center for Human Evolution and Biohistory Research, has formulated a globally-applicable ethical code for research of ancient human DNA. The significant increase throughout the last decade in research of ancient DNA extracted from human remains, and its effects on archeology and other fields, created a need to formulate a dedicated ethical standard that will guide researchers in their work.

Sixty-four international researchers from different fields – archeology, anthropology, curatorship, archeo-genetics and paleo-genetics – from 31 different countries, among them TAU anthropologist and paleo-geneticist Dr. Viviane Slon, took part in the formulation of the ethical code. The ethical code was recently published in the prestigious journal Nature.

Interdisciplinary and International Cooperation

Dr. Slon, who is also a member of Tel Aviv University’s Shmunis Family Anthropology Institute, explains that ancient DNA research has unique aspects, which raise the need for ethical regulations. The examination of past ancestry can have social and political implications today, and because ancient DNA research deals with people who once lived, they must be treated respectfully.

The newly-written ethical codes encourage minimal damage to the human remains during research processes, and call for cooperation with stakeholders, including any descendants or local communities as well as fellow researchers in other fields – and to respect their point of view.

Dr. Slon says: “The guidelines proposed here encompass all the different stages of research, from planning, through sampling and sharing of data and results, to communicating with our fellow researchers and with the general public. It is an international project born out of a virtual meeting that took place about a year ago, in which there was a wide consensus regarding the need for ethical regulations in this growing field, and here we have the final product.”

“We hope to increase its impact, and we are working to translate the paper into dozens of languages, including Hebrew. Recently, researchers from the Shmunis Family Anthropology Institute and the Dan David Center for Human Evolution and Biohistory Research led the breakthrough research discovering ancient human remains in the vicinity of the Nesher Ramla factory. Due to the foundational principals  laid  for the expansion of the interdisciplinary cooperation in the world of ancient DNA research, we will now be able to maximize the scientific accomplishments in this field, in Israel and throughout the world.”

Featured image: Dr. Viviane Slon (Photo: Fabrizio Mafessoni)

Hitting Rock Bottom?

First meta-analysis of its kind shows warming of Mediterranean Sea causes marine species to migrate.

As has been heavily discussed at the recent the UN Climate Change Conference (COP26) in Glasgow, our entire planet has been warming in recent decades. This process has been particularly marked in the Mediterranean Sea, where the average water temperature rises by one degree every thirty years, and the rate is only accelerating. One of the urgent questions that must be asked is how, if at all, the various species living in the Mediterranean will adapt to this sudden warming.

In recent years, evidence has accumulated that some species have deepened their habitats in order to adapt to global warming, while other studies have found that species are limited in their ability to deepen into cooler water. A new TAU study shows that there are species of marine animals such as fish, crustaceans and mollusks (for example squid) that change their habitats and deepen an average of 55 meters across the climatic gradient of the Mediterranean (spanning a range of 60 C) to live in cooler waters.

The Mediterranean – An Ideal Test Case

“It should be remembered that the Mediterranean was hot in the first place, and now we are reaching the limit of many species’ capacity,” explains Prof. Jonathan Belmaker from the School of Zoology in The George S. Wise Faculty of Life Sciences. “Moreover, the temperature range in the Mediterranean is extreme – cold in the northwest and very hot in the southeast. Both of these factors make the Mediterranean an ideal test case for species’ adaptation to global warming.”

The groundbreaking study was led by PhD student Shahar Chaikin under the supervision of Prof. Jonathan Belmaker, and along with researchers Shahar Dubiner, all from the School of Zoology in The George S. Wise Faculty of Life Sciences and The Steinhardt Museum of Natural History at Tel Aviv University. The results of the study were published in the journal Global Ecology and Biogeography, and have far-reaching implications for both fishing and future marine nature reserves.

Life at the Bottom

Cause for Preparation

The results of the study have many implications for the future, in the Mediterranean and in general, given that the response of each species to rising temperatures can be predicted according to its traits, such as temperature preference. This, for the first time, offers researchers the opportunity to forecast changes in the composition of the marine community, as well as for the public the opportunity to prepare for these changes accordingly.

“Our research clearly shows that species do respond to climate change by changing their depth distribution,” Chaikin concludes, “and when we think about the future, decision-makers will have to prepare in advance for the deepening of species. For example, future marine nature reserves will need to be defined so that they can also provide shelter to species that have migrated to greater depths. And on the other hand, fishing in the future will involve fishing the same fish at greater depths, which means sailing further into the sea and burning more fuel.”

So, How Deep is Our Love?

In the framework of the study, the Tel Aviv University researchers conducted a meta-analysis of data on the depth distribution of 236 marine species collected in previous bottom-trawl surveys. The data collected revealed for the first time that species deepen their minimum depth limits in parallel with warming seawater temperatures, from the west to the east Mediterranean, and on average deepen 55 meters across the Mediterranean (a range of 60 C).

However, the pattern of deepening is not uniform between species: cold-water species were found to deepen significantly more than warm-water species, species that live along a narrow depth range deepen less than species that live along a wide depth gradient, and species that can function within in a wider temperature range deepen more than those who can function only within a narrow temperature range.

“Various studies collect fishing data from trawling – that is, a boat that drags a net along the seabed and collects various species – and these studies often also measure the depth at which the species were caught in the net,” says Shahar Chaikin. “We cross-referenced these data with water temperature data, and by analyzing 236 different species we came to a broad and compelling conclusion: there has been a deepening of the depth limits of species’ habitats. The minimum depths for species in the Mediterranean are getting deeper, while the maximum depths remain stable. The deepening effect was found to be more significant among cold-water species. In contrast, there are species that function within a narrow temperature range and at a certain depth that deepen much less, probably because they cannot survive in deeper water.”

 

“Even if species deepen to escape the warm waters and this rapid adaptation helps them, there is still a limit – and that limit is the seabed,” adds Prof. Belmaker. “We are already seeing deep-sea fish like cod whose numbers are declining, probably because they had nowhere deeper to go.”

Seahorses – Slow, but Fierce

Terrible swimmers with incredible preying capability.

Seahorses are not exactly Olympic swimmers, in fact they’re considered to be particularly poor swimmers. Despite being relatively slow, however, they are adept at preying on small, quick-moving animals. In a new study conducted at Tel Aviv University, researchers have succeeded in characterizing the incredible preying capability of seahorses, discovering that they can move their head up at the incredible speed of 0.002 seconds. The rapid head movement is accompanied by a powerful flow of water that snags their prey right into the seahorse’s mouth. How was this spring mechanism formed? When did it develop? The researchers hope the recent study will lead to further studies designed to help solve the riddle of spring fish.

The study was led by Prof. Roi Holzman and the doctoral student Corrine Jacobs of the School of Zoology at The George S. Wise Faculty of Life Sciences and the Steinhardt Museum of Natural History at Tel Aviv University, and was conducted at the Interuniversity Institute for Marine Sciences in Eilat. The study was published in the Journal of Experimental Biology.

Springing to Action

The researchers explain that seahorses are fish that possess unique properties such as male ‘pregnancy’, square tail vertebrae, and of course the unique eating system. For most of the day, seahorses are anchored with their tail to seaweeds or corals with their head tilted downward, close to their body. However, when they detect prey passing over them, they lift their head at incredible speed and catch it. According to Prof. Holzman, while preying, seahorses turn their body into a kind of spring: using their back muscles, they stretch an elastic tendon, and use their neck bones as a ‘trigger’, just like a crossbow. The result is faster than even the fastest muscle contraction found anywhere in the animal world.

However, until now it was not clear how the spring-loaded mechanism enabled seahorses to actually eat. Just as anyone who tries to remove a fly from a cup of tea knows, water is a viscous medium and the fish needs to open its mouth to create a flow that draws the prey in. But how do seahorses coordinate snagging in prey with their head movement?

In their recent study, researchers from Tel Aviv University succeeded in characterizing and quantifying seahorse movement by photographing their attack at a speed of 4,000 images per second, and using a laser system for imaging water flows. This measurement showed that the ‘crossbow’ system serves two purposes: facilitating head movement and generating high velocity suction currents – 10 times faster than those of similar-sized fish. These advantages enable seahorses to catch particularly elusive prey.

Evolution of the Spring Mechanism

The new measurements also help shed light on the ecology of various species of seahorses, distinguished from each other by the length of their noses. “Our study shows that the speed of head movement and suction currents are determined by the length of a seahorse’s nose”, Prof. Holzman added. “From the evolutionary aspect, seahorses must choose between a short nose for strong suction and moderate head raising, or a long nose for rapid head raising and weaker suction currents. This choice, of course, corresponds to the available diet: long-nosed species catch smaller, quicker animals whereas short-nosed species catch heavier, more ponderous ones.”

 

Prof. Roi Holzman hopes the recent study will lead to further studies to help solve the riddle of spring fish

According to Prof. Holzman, seahorses are not the only instance of the impressive spring mechanism. Actually, seahorses are counted among the family of fish bearing the appropriate scientific name Misfit Fish, including species such as alligator pipefish, shrimpfish, and cornetfish or flutemouths.

“These fish are called that because of their odd shape which enables stretching their body into a spring. The big question applies to the evolution of the spring mechanism, how it was formed and when it developed. I hope our recent study will lead to further studies designed to help solve the riddle of spring fish”. 

A New Tool for Combating Discrimination

After decade long study, the Kantor Center has published a special book edition on legislation against discrimination and racism around the globe.

The Kantor Center for the Study of Contemporary European Jewry recently completed writing four extensive volumes of legislation covering existing anti-discrimination laws on the grounds of racism, religion and ethnicity in all 195 countries of the world. Entitled “Legislating for Equality – a Multinational Collection of Non-Discrimination Norms.” It is the first time that researchers have mapped, examined and compared policies aimed at eradicating discrimination in each country.

The comprehensive initiative, led by Adv. Talia Naamat, legal researcher at the Kantor Center, involved in-depth examination of the countries’ constitutions, as well as international conventions and agreements. Universities and researchers from around the world contributed. Recognizing the value this work brings to the global stage, former Director-General of UNESCO Irina Bokova wrote the introduction to the volumes published by Brill, one of the world’s leading law book publisher.

From Antisemitic Laws to Racist Laws

“The study was born out of a practical need to combat antisemitism,” says Naamat, the editor-in-chief of the volumes. “We started working on it in 2011, when researchers approached us with questions about antisemitic legislation following a seminar on the subject. We’d receive questions such as where Holocaust denial was allowed and where it was forbidden.” Prof. Dina Porat, Head of the Kantor Center, recalls “One of the researchers mentioned the law in his country, when another researcher jumped in and pointed out that in his country the situation was different.”

The research quickly expanded, “We realized that we needed to review the information in a broader manner, looking at the general prohibition of discrimination and the combatting of all types of racism. Thus we began compiling the relevant constitutional clauses, parts of penal codes as well as the language of specific laws,” explains Naamat.   

In the volumes, the authors sorted the countries according to continents. Obtaining the information was more straightforward for some continents than others. The highly organized and digitized nature of the information gathered from European countries made the research easier, while for continents like Africa and Asia they had to win collaborations with universities and other bodies in order to obtain the necessary data, translate the information to English and obtain the required translation certificates. Many of the laws had never before been published in English.

Israel and the World

Legislation, of course, does not necessarily reflect the actual situation on ground. The researchers consulted with annual reports from the U.S. State Department, among others, to assess the situation in each country. “We addressed such discrepancies in the footnotes. For example, if the constitution in a particular country stipulates that every citizen has the right to political organization, but we know the actual situation on ground is catastrophic and that there’s currently a civil war taking place there, then we’d address this in the comments,” notes Naamat.

And what is the current situation here in Israel? “We like to compare ourselves to Europe, and we do operate with a high standard for freedom of expression in Israel. The enforcement, however, is more severe in Europe, and the whole discourse is conducted differently here,” says Naamat. Porat adds, “While calling another person a ‘Nazi’ in Europe is an offence which may lead to punishment, here in Israel a person can use the word [unpunished] from morning to evening. We have this absurd situation whereby we [Israelis] demand that Europeans enforce it, while we do not have a single law on the subject ourselves.” 

The Israeli discourse is more open than in Europe – for better or worse

Human Rights Violations Against Witches and Persons with Albinism

Our research showed that culture, form of government and attitudes towards religion greatly influenced legislation. “We were surprised to see that there are countries with harsh realities on ground, but with good constitutions. The constitutions of Saudi Arabia, Libya and Iran, for instance, appear very enlightened. If you had read the constitutions of any of these countries without preexisting knowledge about the country, you could mistake it for being all about equality and solidarity”, says Porat.

The degree of separation between state and religion was also a significant factor. “For example, in Iran where the Sharia law, a religious law, has been incorporated into the country’s otherwise secular laws. Other religious principles can be found, such as permitting the murder of a person who has raped or harmed another person,” notes Porat.

The volume about African countries shows how religion and culture influence legislation, for example through the persecution of witches and albino hunting. “We may expect legislation to be something that represents net justice, while in practice it is a product of what you and I believe and believe in. For example, there are religious principles that contradict human rights and the freedom of religion and worship. We have seen laws prohibiting the persecution of witches and albinos (there are places where being in the possession of an albino person’s limbs is considered a blessing), and the fundamental question arose as to when religious worship should be allowed and when religion violates human rights,” Naamat and Porat explain.

 

Leave them alone. An albino child anno 2021.

Legislation is Dynamic

The good news is that in most countries of the world laws are constantly being renewed and updated. The circumstances for enacting new laws vary. In 2008, the EU announced that all member states must align and enact anti-discrimination laws, which led to widespread legislation across the continent.

Porat and Naamat point to growing global immigration over the last decade as one of the main influences on changes in legislation: “We observed this in the early 1990s, when a big wave of immigration began. The USSR disintegrated, Germany united, waves of immigrants changed their direction and, and new questions emerged: Who is an immigrant? Who is a refugee? Who is a foreign worker? Who deserves what? The legislation was expanded and many new laws were introduced.”

“As immigration grew, so did racism, discrimination, and harsh expressions. The mass immigration to Germany led to the rise of neo-Nazism and the extreme right, which is actually a counter-reaction of those who ask ‘What about us? You care about the immigrants but what will happen with us?’” says Naamat.

Where Are We Headed?

The situation on ground may not look particularly bright in many places. However, these new books make the information accessible for all, openly presenting what is happening all over the world. The anthology could serve as a source of hope and pave the way for revolutions. “We are offering a tool that allows countries to compare their laws with those of other countries, and improve them. Such activity started as soon as the books were published. The secretary of the Jewish community in Greece received a copy and went on to check the existing laws in Europe against Holocaust denial. He told us that the information helped him promote an amended law in his country. And this will happen in other places,” predicts Porat.

 

Israel’s Supreme Court President Justice Esther Hayut receives the four volumes.

 

Porat presented the four volumes to Supreme Court President Justice Esther Hayut during a special visit to the country’s highest judicial officer. Chief Justice Hayut congratulated Prof. Porat on the academic achievement, noting that it adds an important dimension to the war on racism and discrimination against various peoples and groups in the world.

The meeting was also attended by former president of Tel Aviv University Professor Emeritus Yoram Dinstein who chaired the scientific committee that accompanied the work; former Deputy President of the Supreme Court Justice Prof. Elyakim Rubinstein and Supreme Court Justice Daphne Barak-Erez who were members of the accompanying committee; Adv. Talia Naamat and Celia and Jack Michonik who generously supported the work.

“Thank you, Your Excellency, on behalf of everyone present, for the time you have devoted to us and for the interest which you have shown our work. We hope that these volumes will contribute, albeit modestly, to the fight against racism-based discrimination in the world – an evil which is present in many countries and societies. And that’s consistent with the spirit of the values that our Supreme Court, of which we are proud, leads in your leadership,” said Prof. Porat excitedly. 

Featured image: Prof. Dina Porat with the four volumes

Facebook And WhatsApp Are Changing The Sexual Abuse Attitude In Israel’s Hasidic Community

New study at Tel Aviv University reveals deep processes occurring in this sector over the past few years.

After years of silencing and concealment, covering up and repressing the issue, a new TAU study reveals that, over the past few years, more exposure to media and higher education has increased the awareness of the consequences of sexual abuse for its victims and the need for therapeutic intervention and prevention of future abuse. The study was conducted by Dr. Sara Zalcberg of TAU’s Religious Studies Program, Lester and Sally Entin Faculty of Humanities, and presented at the ‘Haredi Society in Israel’ conference of the Shandong University and Tel Aviv University Joint Institute for Israel and Judaism Studies.

Weakening The ‘Conspiracy of Silence’

Dr. Zalcberg: “The study’s findings indicate a trend of significant change in the Haredi society’s attitude toward sexual abuse. About a decade ago, many of the victims in this sector were not even aware of the fact that they had been sexually abused; Many parents didn’t know that sexual abuse of children even existed; And Haredi society as a whole was characterized by a three-way culture of silence – involving the victim, his/her family and the community and leadership. According to our study’s findings this ‘conspiracy of silence’ has gradually weakened in recent years, with evidence for a significant rise in both awareness and discourse regarding sexual abuse and its consequences.” The study comprised interviews with professionals working with the Haredi population, including in cases of sexual abuse, as well as activists involved in community safety, parents of children who had been sexually abused and a woman who had been sexually abused herself when she was a child. According to Dr. Zalcberg, the study has identified a gradual process, starting with the exposure of the Haredi sector to the job market, to education and to the virtual world, alongside the emergence of grassroots activism – from inside Haredi society. These have engendered a growing openness in discourse about sexuality, the body and intimacy, as well as an increase in the numbers of therapeutic and welfare professionals coming from the Haredi community – ultimately generating the first cracks in the high walls of reluctance to admit and address sexual abuse in Haredi society.

“Once Exposed to the Internet, They are Exposed to Everything”

According to the study, the changes are manifested in several ways. First, a growing and unprecedented use of the online arena, including WhatsApp and Facebook, for discussing and addressing sexual abuse. One interviewee in the study noted: “The Haredi sector is exposed to the internet, and once exposed to the internet they are exposed to everything. Information is more accessible.” A social worker in a Haredi city added: “Haredi women in the therapeutic professions use the internet to disseminate information about sexual abuse, safety and therapy, and so the Haredi community learns about the issue.” The study also identifies change among families and parents of victims, manifested in the demand for prevention workshops that provide tools for recognizing and preventing sexual aggression. The supreme value of defending the community against any outside influence or criticism is being replaced by care for the welfare of families and children. This change has also led to a conceptual shift in a large portion of the Haredi leadership, who now recognize the abuse and its victims and promote the connection with welfare authorities. Dr. Zalcberg emphasizes that the change can even be discerned in the more insular and conservative groups within Haredi society. As Chezi, a Haredi social worker working with the Haredi population in one of the social services, commented: “We see more openness even in the conservative community. Hassidic communities that usually don’t turn to us (to the social services), now come when there’s a case of sexual abuse. They understand that this is a serious matter.” At the same time, as the study points out, despite the significant processes taking place in Haredi society, there are still considerable gaps in both awareness and addressing the phenomenon and its consequences. Dr. Zalcberg: “Despite the change taking place in Haredi society with regard to discussing and addressing sexual abuse, a great deal more still needs to be changed. Both discourse and awareness should be enhanced, preventive measures must be advanced, and the rates of reporting abuse and asking for professional intervention should be increased. There is urgent need for mapping families and communities who don’t have sufficient access to information and services, and for promoting specifically tailored responses.”

Are We Getting to the Root of Cancer?

Groundbreaking discovery that plant roots grow in a spiral motion inspires search for similar motion in cancer cells.

In an interdisciplinary research project carried out at Tel Aviv University, researchers from the School of Plant Sciences affiliated with The George S. Wise Faculty of Life Sciences collaborated with their colleagues from the Sackler Faculty of Medicine in order to study the course of plant root growth. Aided by a computational model constructed by cancer researchers studying cancer cells, adapted for use with plant root cells, they were able to demonstrate, for the first time in the world, and at the resolution of a single cell, that the root grows with a screwing motion – just like a drill penetrating a wall. In the wake of this study, the cancer researchers conjecture that cancer cells, too, are assisted by a spiral motion in order to penetrate healthy tissue in the environment of the tumor, or to create metastases in various organs of the body. The research was led by Prof. Eilon Shani from the School of Plant Sciences and Food Security and Prof. Ilan Tsarfaty from the Department of Clinical Microbiology and Immunology at Tel Aviv University, and was conducted in collaboration with researchers from the USA, Austria and China. The article was published in March 2021 in the acclaimed journal Nature Communications.

Significant Advance in Plant Research – and in the War on Cancer?

The researchers in Prof. Shani’s group, led by Dr. Yangjie Hu, used as a model the plant known as Arabidopsis. They marked the nuclei of the root cells with a fluorescent protein and observed the growing process and movement of the cells at the root tip through a powerful microscope – approximately 1000 cells in each movie. Furthermore, in order to examine what causes and controls the movement, they focused on a known hormone named auxin, which regulates growth in plants. They built a genetic system that enables activation of auxin production (like a switch) in a number of selected cells-types, and then monitored the influence of the on/off mechanism, in four dimensions – the three spatial dimensions and the dimension of time. After each instance of auxin biosynthesis, each of the thousand cells was video recorded for a period of 6 to 24 hours, thus an enormous amount of data accumulated.

WATCH: The process of growth and movement of cells at the root tip using a microscope

For the next stage, the researchers were aided by the computational tools provided by Prof. Tsarfaty, which had been developed in his laboratory for the purpose of monitoring the development of cancerous growths. They used these tools to analyze the imaging data obtained in the study. Thus they were actually able, for the first time, to observe with their own eyes the corkscrew movement of the root, as well as to precisely quantify and chart some 30 root growth parameters relating to time and space – including acceleration, length, changes in cell structure, coordination between cells during the growth process and velocity – for each one of the thousand cells at the root tip. Using fluorescent reporters, the findings even allowed them to precisely assess the movement and the influence of the auxin on the root, and the way in which it controls the growth process. Prof. Shani: “The computational tools that were developed for cancer research have enabled us, for the first time, to precisely measure and quantify the kinetics of growth and to reveal the mechanisms that control it at the resolution of a single cell. By this they have significantly advanced plant research, an area of utmost importance for society – both from an environmental point of view and in terms of agriculture and feeding the population.” Prof. Tsarfaty adds: “This was a synergetic collaboration that benefited and enlightened both parties. In plants, processes take place much more rapidly, and therefore constitute an excellent model for us. In consequence of the findings provided by this plant study, we are presently examining the possibility of a similar screw-like motion in cancer cells and in metastases, in the course of their penetration into adjacent healthy tissues.”

Tel Aviv’s Ecological Oasis: The Yehuda Naftali Botanic Garden at TAU

A donor-supported renovation focuses on research, facilities and visitor access.

By Lindsey Zemler

TAU’s Yehuda  ​Naftali Botanic Garden is a Tel Aviv oasis for all, a collaborative research hub for plant scientists, engineers and neuroscientists, as well as a beautiful urban nature site that welcomes schoolchildren, soldiers and the general public and numbers among the city’s top tourist attractions.

In the last few months, the Garden has been undergoing a massive rejuvenation and enhancement program.

“Thanks to the generous support of Mr. Yehuda Naftali, this long-awaited renovation marks a significant step forward in our mission to be at the cutting edge of botanical research, education and conservation in Israel,” says Prof. Abdussalam Azem, Dean of the George S. Wise Faculty of Life Sciences, to which the Garden belongs. “This project brings us to the next level in improving infrastructure and access.”

Path construction in progress. Photo: Rafael Ben-Menashe.

A priority in planning the renovations, which are almost complete, was to increase access to all corners of the 34-dunam (8-acre) site, including to school groups, families, researchers, and students. This involved making the paths easier to navigate with wheelchairs, strollers, or groups.

Upon entering, the visitor will enjoy seeing native flora in the new beds adjacent to the garden’s western boundary fence, which are placed according to where they are found in Israel, from north to south.  The acacia tree planted by Mr. Naftali at the Garden’s inauguration in 2019 can be found there, growing nicely.

A variety of paths throughout the Garden. (Left): A natural blanket of pine needles is reminiscent of a walk through the Carmel Forest. Photos: Rafael Ben-Menashe.

The main pathways are wide, paved and comfortable for walking in groups. Smaller paths branch out among various habitats to allow visitors an immersive nature experience. They are all designed to emulate natural processes; sometimes a section is left unpaved for water flow.

Water pond with newly added wooden deck. Photo: Moshe Bedarshi.

Rainfall naturally flows downhill and arches in a waterfall to fill a pond, where the addition of wooden decks allows the visitor to stand comfortably at the edge of the water to view wetland plant species.

“When we planned the renovations, we put a lot of thought into the best visitor experience: to create a feeling of being transported to a nature reserve and being able to experience it from close range,” explained Kineret Manevich, Public Outreach Coordinator of the Garden.

New irrigation control center (left) and irrigation pipe (right) in the pine forest habitat. Photos (left) by Rafael Ben-Menashe and (right) by Moshe Bedarshi.

A new computer-controlled irrigation system is part of the critical infrastructure changes in the renovation plan. A large, complex network of pipes provides thousands of plants with essential water.

(Left): Rare plants being cared for in the nursery and (right) image of geo-mapping software. Photo (left) by Rafael Ben-Menashe and (right) courtesy of the Botanic Garden.

The Garden is also an active research center, where every plant is mapped and monitored, creating a robust database of botanical research. In addition, rare plants are rehabilitated and returned to nature.

The Garden offers a complete sensory experience, full of texture, color and shapes.

The area is a living ecosystem providing refuge to plants, animals, and of course, humans seeking nature without leaving Tel Aviv. The Yehuda Naftali Botanic Garden will be open to the public, and together with the adjacent Steinhardt Museum of Natural History will welcome visitors of all kinds.

Finding Humor in Imperfection

The “TAU Review” held a Zoom interview with well-known Israeli comedian, writer and TV and radio host, Einav Galili, who earned her BA in psychology and arts from TAU in 2001.
By Melanie Takefman “Holocaust jokes are a wonderful thing,” says TAU alumna Einav Galili. “When you laugh at something, it doesn’t dishonor it; it’s another way of dealing with something that’s impossible to deal with…the Holocaust intrigues me and in that way it is totally mine to laugh about.” By contrast, if a German told a Holocaust joke, “I would shoot him,” she says jokingly, maintaining her trademark poker face. “Comedy is a way to expose our dark side without anyone dying.” For decades, Galili has brought a sharp, intellectual and hilariously wry voice to Israeli media.  Yet, with her influence comes responsibility: Galili believes that she has a role to play in shaping public discourse. “It’s part of my job to extract topics from their conventional molds and clichés and forge something more complex,” she says. In Israel, “you must be radical to have a presence…People want short, extreme and click-baity. I often try to give a fuller picture….I try very hard not to be predictable.” The same is true about the range of subjects she broaches on the morning radio show she co-hosts: from politics to the connection between Koala and human diseases. For Galili, comedic and serious content need not be separated. “The most interesting people are those whose humor is laced with pain and whose pain is laced with humor. In the end, it’s all different layers of the same thing.” Yet, sometimes being funny comes at a cost. As a main panelist on one of the country’s longest-running TV satires, State of the Nation (later renamed Back of the Nation), Galili is no stranger to controversy. “What we say makes people uncomfortable…..It’s a program that’s a big headache to support and maintain. You have to withstand pressure and you receive angry phone calls.” Still, she has never been censored. With governments around the world cracking down on journalists and limiting freedom of speech, she doesn’t take that for granted and considers herself “spoiled” in this respect.  At the same time, she says that viewers themselves often quash serious programming. “You come home in the evening. Life is tough…it’s hard to make a living…there are a million things to deal with. You don’t have the energy for another burdensome investigation about violence against women. You want Netflix!” she says. “I can understand them.” Exposing national neuroses That being said, satire is “like the vital signs of a human body. If we don’t have it, it’s like declaring death.” ​​​Humor is especially important during crises such as the Corona pandemic. “Sometimes humor can be divisive; one groups laughs at another. But when people laugh about a common experience such as Corona, it brings people together.” She adds, Humor exposes the neuroses that characterize Israeli society….there is a very interesting dance with humor around taboos. It helps determine what’s legitimate and what’s not.”   Photo: Adi Orni In addition to her radio show and Back of the Nation, she hosts the Israeli version of the BBC TV program Room 101, in which she interviews Israeli personalities about their biggest fears or pet peeves. She also lectures about humor and writes newspaper columns. She recently produced a documentary about the anti-aging industry. Galili is one of several well-known female comedians in Israel, but women are still the minority in the field. An avowed feminist, she says that she insists on having at least one female writer on the Back of the Nation team. What separates her from her male counterparts, she says, are the jokes she doesn’t make. She will never make a joke about a woman being old or ugly or fat, she says. ”It’s not in my agenda.”
She will, however, soliloquize about her children’s hamsters, riffing on their proclivity for reproduction and what happened when she had to eulogize one of two identical pets (she didn’t know which one died.)

​Her various endeavors have given her insights into the human psyche. ”We live in a society preoccupied with perfection: We strive to look perfect, to make a good impression, to portray ourselves as more than what we are, more beautiful, younger, more confident, more successful in our careers, taller, skinnier.”

To her, perfect is boring. It is exactly in imperfection“the defects and the cracks”that she finds her most engaging and inclusive material.

Drawing on academic training Analyses like these exemplify how psychology permeates Galili’s many professional roles. Her TAU studies left an imprint on her in other ways too. Studying at the University taught her discipline and the value of hard work. In academia, and particularly in psychology, a very competitive program, everything is systematic, she says. If you put in the effort, you see results. Her studies also armed her with critical thinking skills—how to differentiate between reliable and unreliable information—an important ability in the era of social media and fake news. Galili recalls her time at TAU as a very enjoyable and enriching experience. She was completely immersed in her studies, alongside “amazing” classmates and inspiring professors. She remembers Prof. Ina Weiner, a “fascinating” professor who taught her honors psychology, and art historian Dr. Henry Unger, who “taught me elementary terms about the arts world. It was precisely enough to know what to look for.” As an alumna, Galili is one of 85,000 members of the TAU Alumni Organization, which is celebrating its fifth anniversary this year, under the direction of Sigalit Ben Hayoun. The Organization’s goal is to leverage the influence of TAU alumni as a positive force in Israeli society and serve alumni through shared knowledge, networking and opportunities. Upon receiving her BA, Galili completed the coursework for a master’s degree in psychology, but never submitted a thesis. Even though she is very happy with where her career has taken her, she has never stopped dreaming of returning to TAU to complete her MA. We hope she realizes that dream. Featured image: Einav Galili. Photo: Shay Bachar.

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