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Tag: Life Sciences

Facebook And WhatsApp Are Changing The Sexual Abuse Attitude In Israel’s Hasidic Community

New study at Tel Aviv University reveals deep processes occurring in this sector over the past few years.

After years of silencing and concealment, covering up and repressing the issue, a new TAU study reveals that, over the past few years, more exposure to media and higher education has increased the awareness of the consequences of sexual abuse for its victims and the need for therapeutic intervention and prevention of future abuse. The study was conducted by Dr. Sara Zalcberg of TAU’s Religious Studies Program, Lester and Sally Entin Faculty of Humanities, and presented at the ‘Haredi Society in Israel’ conference of the Shandong University and Tel Aviv University Joint Institute for Israel and Judaism Studies.

Weakening The ‘Conspiracy of Silence’

Dr. Zalcberg: “The study’s findings indicate a trend of significant change in the Haredi society’s attitude toward sexual abuse. About a decade ago, many of the victims in this sector were not even aware of the fact that they had been sexually abused; Many parents didn’t know that sexual abuse of children even existed; And Haredi society as a whole was characterized by a three-way culture of silence – involving the victim, his/her family and the community and leadership. According to our study’s findings this ‘conspiracy of silence’ has gradually weakened in recent years, with evidence for a significant rise in both awareness and discourse regarding sexual abuse and its consequences.” The study comprised interviews with professionals working with the Haredi population, including in cases of sexual abuse, as well as activists involved in community safety, parents of children who had been sexually abused and a woman who had been sexually abused herself when she was a child. According to Dr. Zalcberg, the study has identified a gradual process, starting with the exposure of the Haredi sector to the job market, to education and to the virtual world, alongside the emergence of grassroots activism – from inside Haredi society. These have engendered a growing openness in discourse about sexuality, the body and intimacy, as well as an increase in the numbers of therapeutic and welfare professionals coming from the Haredi community – ultimately generating the first cracks in the high walls of reluctance to admit and address sexual abuse in Haredi society.

“Once Exposed to the Internet, They are Exposed to Everything”

According to the study, the changes are manifested in several ways. First, a growing and unprecedented use of the online arena, including WhatsApp and Facebook, for discussing and addressing sexual abuse. One interviewee in the study noted: “The Haredi sector is exposed to the internet, and once exposed to the internet they are exposed to everything. Information is more accessible.” A social worker in a Haredi city added: “Haredi women in the therapeutic professions use the internet to disseminate information about sexual abuse, safety and therapy, and so the Haredi community learns about the issue.” The study also identifies change among families and parents of victims, manifested in the demand for prevention workshops that provide tools for recognizing and preventing sexual aggression. The supreme value of defending the community against any outside influence or criticism is being replaced by care for the welfare of families and children. This change has also led to a conceptual shift in a large portion of the Haredi leadership, who now recognize the abuse and its victims and promote the connection with welfare authorities. Dr. Zalcberg emphasizes that the change can even be discerned in the more insular and conservative groups within Haredi society. As Chezi, a Haredi social worker working with the Haredi population in one of the social services, commented: “We see more openness even in the conservative community. Hassidic communities that usually don’t turn to us (to the social services), now come when there’s a case of sexual abuse. They understand that this is a serious matter.” At the same time, as the study points out, despite the significant processes taking place in Haredi society, there are still considerable gaps in both awareness and addressing the phenomenon and its consequences. Dr. Zalcberg: “Despite the change taking place in Haredi society with regard to discussing and addressing sexual abuse, a great deal more still needs to be changed. Both discourse and awareness should be enhanced, preventive measures must be advanced, and the rates of reporting abuse and asking for professional intervention should be increased. There is urgent need for mapping families and communities who don’t have sufficient access to information and services, and for promoting specifically tailored responses.”

Are We Getting to the Root of Cancer?

Groundbreaking discovery that plant roots grow in a spiral motion inspires search for similar motion in cancer cells.

In an interdisciplinary research project carried out at Tel Aviv University, researchers from the School of Plant Sciences affiliated with The George S. Wise Faculty of Life Sciences collaborated with their colleagues from the Sackler Faculty of Medicine in order to study the course of plant root growth. Aided by a computational model constructed by cancer researchers studying cancer cells, adapted for use with plant root cells, they were able to demonstrate, for the first time in the world, and at the resolution of a single cell, that the root grows with a screwing motion – just like a drill penetrating a wall. In the wake of this study, the cancer researchers conjecture that cancer cells, too, are assisted by a spiral motion in order to penetrate healthy tissue in the environment of the tumor, or to create metastases in various organs of the body. The research was led by Prof. Eilon Shani from the School of Plant Sciences and Food Security and Prof. Ilan Tsarfaty from the Department of Clinical Microbiology and Immunology at Tel Aviv University, and was conducted in collaboration with researchers from the USA, Austria and China. The article was published in March 2021 in the acclaimed journal Nature Communications.

Significant Advance in Plant Research – and in the War on Cancer?

The researchers in Prof. Shani’s group, led by Dr. Yangjie Hu, used as a model the plant known as Arabidopsis. They marked the nuclei of the root cells with a fluorescent protein and observed the growing process and movement of the cells at the root tip through a powerful microscope – approximately 1000 cells in each movie. Furthermore, in order to examine what causes and controls the movement, they focused on a known hormone named auxin, which regulates growth in plants. They built a genetic system that enables activation of auxin production (like a switch) in a number of selected cells-types, and then monitored the influence of the on/off mechanism, in four dimensions – the three spatial dimensions and the dimension of time. After each instance of auxin biosynthesis, each of the thousand cells was video recorded for a period of 6 to 24 hours, thus an enormous amount of data accumulated.

WATCH: The process of growth and movement of cells at the root tip using a microscope

For the next stage, the researchers were aided by the computational tools provided by Prof. Tsarfaty, which had been developed in his laboratory for the purpose of monitoring the development of cancerous growths. They used these tools to analyze the imaging data obtained in the study. Thus they were actually able, for the first time, to observe with their own eyes the corkscrew movement of the root, as well as to precisely quantify and chart some 30 root growth parameters relating to time and space – including acceleration, length, changes in cell structure, coordination between cells during the growth process and velocity – for each one of the thousand cells at the root tip. Using fluorescent reporters, the findings even allowed them to precisely assess the movement and the influence of the auxin on the root, and the way in which it controls the growth process. Prof. Shani: “The computational tools that were developed for cancer research have enabled us, for the first time, to precisely measure and quantify the kinetics of growth and to reveal the mechanisms that control it at the resolution of a single cell. By this they have significantly advanced plant research, an area of utmost importance for society – both from an environmental point of view and in terms of agriculture and feeding the population.” Prof. Tsarfaty adds: “This was a synergetic collaboration that benefited and enlightened both parties. In plants, processes take place much more rapidly, and therefore constitute an excellent model for us. In consequence of the findings provided by this plant study, we are presently examining the possibility of a similar screw-like motion in cancer cells and in metastases, in the course of their penetration into adjacent healthy tissues.”

Tel Aviv’s Ecological Oasis: The Yehuda Naftali Botanic Garden at TAU

A donor-supported renovation focuses on research, facilities and visitor access.

By Lindsey Zemler

TAU’s Yehuda  ​Naftali Botanic Garden is a Tel Aviv oasis for all, a collaborative research hub for plant scientists, engineers and neuroscientists, as well as a beautiful urban nature site that welcomes schoolchildren, soldiers and the general public and numbers among the city’s top tourist attractions.

In the last few months, the Garden has been undergoing a massive rejuvenation and enhancement program.

“Thanks to the generous support of Mr. Yehuda Naftali, this long-awaited renovation marks a significant step forward in our mission to be at the cutting edge of botanical research, education and conservation in Israel,” says Prof. Abdussalam Azem, Dean of the George S. Wise Faculty of Life Sciences, to which the Garden belongs. “This project brings us to the next level in improving infrastructure and access.”

Path construction in progress. Photo: Rafael Ben-Menashe.

A priority in planning the renovations, which are almost complete, was to increase access to all corners of the 34-dunam (8-acre) site, including to school groups, families, researchers, and students. This involved making the paths easier to navigate with wheelchairs, strollers, or groups.

Upon entering, the visitor will enjoy seeing native flora in the new beds adjacent to the garden’s western boundary fence, which are placed according to where they are found in Israel, from north to south.  The acacia tree planted by Mr. Naftali at the Garden’s inauguration in 2019 can be found there, growing nicely.

A variety of paths throughout the Garden. (Left): A natural blanket of pine needles is reminiscent of a walk through the Carmel Forest. Photos: Rafael Ben-Menashe.

The main pathways are wide, paved and comfortable for walking in groups. Smaller paths branch out among various habitats to allow visitors an immersive nature experience. They are all designed to emulate natural processes; sometimes a section is left unpaved for water flow.

Water pond with newly added wooden deck. Photo: Moshe Bedarshi.

Rainfall naturally flows downhill and arches in a waterfall to fill a pond, where the addition of wooden decks allows the visitor to stand comfortably at the edge of the water to view wetland plant species.

“When we planned the renovations, we put a lot of thought into the best visitor experience: to create a feeling of being transported to a nature reserve and being able to experience it from close range,” explained Kineret Manevich, Public Outreach Coordinator of the Garden.

New irrigation control center (left) and irrigation pipe (right) in the pine forest habitat. Photos (left) by Rafael Ben-Menashe and (right) by Moshe Bedarshi.

A new computer-controlled irrigation system is part of the critical infrastructure changes in the renovation plan. A large, complex network of pipes provides thousands of plants with essential water.

(Left): Rare plants being cared for in the nursery and (right) image of geo-mapping software. Photo (left) by Rafael Ben-Menashe and (right) courtesy of the Botanic Garden.

The Garden is also an active research center, where every plant is mapped and monitored, creating a robust database of botanical research. In addition, rare plants are rehabilitated and returned to nature.

The Garden offers a complete sensory experience, full of texture, color and shapes.

The area is a living ecosystem providing refuge to plants, animals, and of course, humans seeking nature without leaving Tel Aviv. The Yehuda Naftali Botanic Garden will be open to the public, and together with the adjacent Steinhardt Museum of Natural History will welcome visitors of all kinds.

Finding Humor in Imperfection

The “TAU Review” held a Zoom interview with well-known Israeli comedian, writer and TV and radio host, Einav Galili, who earned her BA in psychology and arts from TAU in 2001.
By Melanie Takefman “Holocaust jokes are a wonderful thing,” says TAU alumna Einav Galili. “When you laugh at something, it doesn’t dishonor it; it’s another way of dealing with something that’s impossible to deal with…the Holocaust intrigues me and in that way it is totally mine to laugh about.” By contrast, if a German told a Holocaust joke, “I would shoot him,” she says jokingly, maintaining her trademark poker face. “Comedy is a way to expose our dark side without anyone dying.” For decades, Galili has brought a sharp, intellectual and hilariously wry voice to Israeli media.  Yet, with her influence comes responsibility: Galili believes that she has a role to play in shaping public discourse. “It’s part of my job to extract topics from their conventional molds and clichés and forge something more complex,” she says. In Israel, “you must be radical to have a presence…People want short, extreme and click-baity. I often try to give a fuller picture….I try very hard not to be predictable.” The same is true about the range of subjects she broaches on the morning radio show she co-hosts: from politics to the connection between Koala and human diseases. For Galili, comedic and serious content need not be separated. “The most interesting people are those whose humor is laced with pain and whose pain is laced with humor. In the end, it’s all different layers of the same thing.” Yet, sometimes being funny comes at a cost. As a main panelist on one of the country’s longest-running TV satires, State of the Nation (later renamed Back of the Nation), Galili is no stranger to controversy. “What we say makes people uncomfortable…..It’s a program that’s a big headache to support and maintain. You have to withstand pressure and you receive angry phone calls.” Still, she has never been censored. With governments around the world cracking down on journalists and limiting freedom of speech, she doesn’t take that for granted and considers herself “spoiled” in this respect.  At the same time, she says that viewers themselves often quash serious programming. “You come home in the evening. Life is tough…it’s hard to make a living…there are a million things to deal with. You don’t have the energy for another burdensome investigation about violence against women. You want Netflix!” she says. “I can understand them.” Exposing national neuroses That being said, satire is “like the vital signs of a human body. If we don’t have it, it’s like declaring death.” ​​​Humor is especially important during crises such as the Corona pandemic. “Sometimes humor can be divisive; one groups laughs at another. But when people laugh about a common experience such as Corona, it brings people together.” She adds, Humor exposes the neuroses that characterize Israeli society….there is a very interesting dance with humor around taboos. It helps determine what’s legitimate and what’s not.”   Photo: Adi Orni In addition to her radio show and Back of the Nation, she hosts the Israeli version of the BBC TV program Room 101, in which she interviews Israeli personalities about their biggest fears or pet peeves. She also lectures about humor and writes newspaper columns. She recently produced a documentary about the anti-aging industry. Galili is one of several well-known female comedians in Israel, but women are still the minority in the field. An avowed feminist, she says that she insists on having at least one female writer on the Back of the Nation team. What separates her from her male counterparts, she says, are the jokes she doesn’t make. She will never make a joke about a woman being old or ugly or fat, she says. ”It’s not in my agenda.”
She will, however, soliloquize about her children’s hamsters, riffing on their proclivity for reproduction and what happened when she had to eulogize one of two identical pets (she didn’t know which one died.)

​Her various endeavors have given her insights into the human psyche. ”We live in a society preoccupied with perfection: We strive to look perfect, to make a good impression, to portray ourselves as more than what we are, more beautiful, younger, more confident, more successful in our careers, taller, skinnier.”

To her, perfect is boring. It is exactly in imperfection“the defects and the cracks”that she finds her most engaging and inclusive material.

Drawing on academic training Analyses like these exemplify how psychology permeates Galili’s many professional roles. Her TAU studies left an imprint on her in other ways too. Studying at the University taught her discipline and the value of hard work. In academia, and particularly in psychology, a very competitive program, everything is systematic, she says. If you put in the effort, you see results. Her studies also armed her with critical thinking skills—how to differentiate between reliable and unreliable information—an important ability in the era of social media and fake news. Galili recalls her time at TAU as a very enjoyable and enriching experience. She was completely immersed in her studies, alongside “amazing” classmates and inspiring professors. She remembers Prof. Ina Weiner, a “fascinating” professor who taught her honors psychology, and art historian Dr. Henry Unger, who “taught me elementary terms about the arts world. It was precisely enough to know what to look for.” As an alumna, Galili is one of 85,000 members of the TAU Alumni Organization, which is celebrating its fifth anniversary this year, under the direction of Sigalit Ben Hayoun. The Organization’s goal is to leverage the influence of TAU alumni as a positive force in Israeli society and serve alumni through shared knowledge, networking and opportunities. Upon receiving her BA, Galili completed the coursework for a master’s degree in psychology, but never submitted a thesis. Even though she is very happy with where her career has taken her, she has never stopped dreaming of returning to TAU to complete her MA. We hope she realizes that dream. Featured image: Einav Galili. Photo: Shay Bachar.

Did climate change cause infections 6,000 years ago?

New study of human skulls finds infections peaked due to high population density, poor hygiene and climate conditions

Researchers at Tel Aviv University have discovered evidence of ear infections in the skull remains of humans living in the Levant some 15,000 years ago. “Our research seeks to determine the impact of our environment on illnesses in different periods,” says lead author Dr. Hila May of the Department of Anatomy and Anthropology at TAU’s Sackler Faculty of Medicine and the Dan David Center for Human Evolution and Biohistory Research at the Faculty of Medicine, located at the Steinhardt Museum of Natural History. “Using advanced technologies and unique methods developed in our lab, we have been able to detect signs of prolonged inflammation in the middle ear.” The researchers found a decline in morbidity as a result of ear infections following the transition from hunting and gathering to farming on account of changes in living conditions. A peak in morbidity, however, was observed in a sedentary population living about 6,000 years ago (Chalcolithic period). Dr. May says the reason for this is twofold: social and environmental: “We know from archaeological excavations of this period, similar to preceding periods, people lived in a communal area where all activities, from cooking to raising livestock, took place. As a result, the population density in the ‘home’ was high, hygiene was poor and they suffered from indoor air pollution. Two other factors known about this period – dietary change, the advent of dairy consumption, and climate change, a dip in temperature and a rise in rainfall, also contributed to the prevalence  of ear infections.”

A story in the skulls

Until the advent of antibiotics in the 20th century, ear infections developed into chronic conditions, or, due to complications, caused permanent loss of hearing or even death. “Ear infections are still a very common childhood ailment, with over 50 percent of young children today still suffering from an ear infection at one point or another,” explains Dr. May. “The reason for this is that the tubes that channel fluid from the middle ear to the mouth are underdeveloped in young children, so fluids that accumulate in the ear ultimately cause inflammation.” “A prolonged ear infection would cause permanent damage to the bony wall of the middle ear, which is remarkably preserved into adulthood, so when we sought to investigate changes in communal health over time in our region, we chose to focus on ear infections, developing a special method for doing so,” she adds. The scientists used a videoscope, a tiny camera mounted at the end of a flexible tube, which they inserted through the ear canal to the middle ear to observe its bony walls. In addition, they scanned skull remains with a high-resolution micro-CT, and also examined the middle ear’s bony wall using a light microscope.

More room, fewer infections

As living conditions improved, morbidity as a result of ear infections dropped, according to the study. “Houses were larger and featured several rooms, including separate areas for specific activities, i.e. the kitchen was set up in a separate room or outside, and livestock were kept in a separate area,” she says. “The change in lifestyle and climate is reflected in a decline in morbidity.” “Our study deals with the impact of the environment and social behavior on morbidity rates, and to do so, we examined a common disease that has accompanied humanity since inception – the ear infection,” concludes Dr. May. “Understanding how diseases appear, spread and disappear throughout human history can help prevent and find solutions to contemporary illnesses. The study clearly points out risk factors and shows how lifestyle changes can affect the incidence of the disease. In both ear infections and COVID-19, social distancing and adherence to hygiene reduced the spread of infection, while close quarters and unhygienic living conditions saw infections spike.”

TAU researchers discover unique, non-oxygen breathing animal

The tiny relative of the jellyfish is parasitic and dwells in salmon tissue.

Researchers at Tel Aviv University have discovered a non-oxygen breathing animal. The unexpected finding changes one of science’s core assumptions about the animal world.A study on the finding was published on February 25 in PNAS by TAU researchers led by Prof. Dorothee Huchon of the School of Zoology at TAU’s George S. Wise Faculty of Life Sciences and Steinhardt Museum of Natural History.The tiny, less than 10-celled parasite Henneguya salminicola lives in salmon muscle. As it evolved, the animal, which is a myxozoan relative of jellyfish and corals, gave up breathing and consuming oxygen to produce energy.

Living without oxygen

“Aerobic respiration was thought to be ubiquitous in animals, but now we confirmed that this is not the case,” Prof. Huchon explains. “Our discovery shows that evolution can go in strange directions. Aerobic respiration is a major source of energy, and yet we found an animal that gave up this critical pathway.”Some other organisms like fungi, amoebas or ciliate lineages in anaerobic environments have lost the ability to breathe over time. The new study demonstrates that the same can happen to an animal — possibly because the parasite happens to live in an anaerobic environment.Its genome was sequenced, along with those of other myxozoan fish parasites, as part of research supported by the U.S.-Israel Binational Science Foundation and conducted with Prof. Paulyn Cartwright of the University of Kansas, and Prof. Jerri Bartholomew and Dr. Stephen Atkinson of Oregon State University.

Reversing what we know about evolution

The parasite’s anaerobic nature was an accidental discovery. While assembling the Henneguya genome, Prof. Huchon found that it did not include a mitochondrial genome. The mitochondria is the powerhouse of the cell where oxygen is captured to make energy, so its absence indicated that the animal was not breathing oxygen.Until the new discovery, there was debate regarding the possibility that organisms belonging to the animal kingdom could survive in anaerobic environments. The assumption that all animals are breathing oxygen was based, among other things, on the fact that animals are multicellular, highly developed organisms, which first appeared on Earth when oxygen levels rose. “It’s not yet clear to us how the parasite generates energy,” Prof. Huchon says. “It may be drawing it from the surrounding fish cells, or it may have a different type of respiration such as oxygen-free breathing, which typically characterizes anaerobic non-animal organisms.” According to Prof. Huchon, the discovery bears enormous significance for evolutionary research.“It is generally thought that during evolution, organisms become more and more complex, and that simple single-celled or few-celled organisms are the ancestors of complex organisms,” she concludes. “But here, right before us, is an animal whose evolutionary process is the opposite. Living in an oxygen-free environment, it has shed unnecessary genes responsible for aerobic respiration and become an even simpler organism.”

TAU study among top 12 most important in the world

Prof. Yoel Rak’s anthropology study was selected by Science Magazine as one of the scientific breakthroughs of the 2019

Each year, Science Magazine, arguably the world’s most prestigious scientific publication, selects 12 groundbreaking studies from around the world, inviting the public to vote for whichever study they consider the most important. This year, the list includes an Israeli study, done in collaboration with Prof. Yoel Rak, a physical anthropologist from the Sackler Faculty of Medicine, led by researchers from the Hebrew University of Jerusalem, in which scientists were able to reconstruct a human profile of a mysterious group known as the Danisovans, using DNA remnants only.

Who are the Denisovans?

The Denisovans are a group of humans who lived in the east and northeast of Asia until a few tens of thousands of year ago, and differed in their characteristics from the Homo sapiens and Neanderthals who were alive at the time. While the Homo sapiens lived mainly in Africa at that time, the Neanderthals settled in Europe and North Asia, where they met with the Danisovans and mixed with them. Until recently, all of our knowledge about this group was based on a few small pieces of bone, and it is believed that the group’s existence would not have been uncovered except for the development of new methods for the extraction, sequencing and analysis of ancient DNA.

The study by Prof. Rak and his colleagues presented an exciting breakthrough: the restoration of a Denisovan’s face using an epigenetic reconstruction method of ancient DNA, taken from the tip of a young woman’s finger, which was found in Siberia in 2008. This is a study of genetic changes that do not occur in the sequence of DNA letters itself, but affect how genes are expressed in each and every cell.

The study will make it possible to understand the various adaptations made by the Danisovans group to its surroundings, and shed light on features that distinguish us, modern humans, from the other human groups that did not survive to modern times.

Alongside Prof. Rak’s study, the competition at Science also included the first photograph of a black hole, a photo of the space rock Ultima Thula, the skeleton of “Lucy’s” ancestor from 3.8 million years ago, long-term treatment for the HIV virus and other studies from the world of medicine.

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