TAU to partner with InnoCan Pharma on revolutionary COVID-19 treatment

Written on |

The technology, which is expected to be administered by inhalation, will be tested on several lung infections

InnoCan Pharma Corporation announced that its wholly-owned subsidiary, InnoCan Pharma Ltd. of Herzliya Israel, has entered into a sponsored research agreement with Ramot at Tel Aviv University to jointly develop a novel, revolutionary approach to treat COVID-19 by using cannabidiol (CBD) loaded exosomes (“CLX”). Under the terms of the Research Agreement, InnoCan and a team led by Prof. Daniel Offen, a leading researcher specializing in Neuroscience and Exosome technology at Tel Aviv University, will collaborate to develop the cell therapy based product on Prof. Offen’s work in the field. InnoCan and Ramot are collaborating on a new, revolutionary exosome-based technology that targets both central nervous system (CNS) indications and the Covid-19 Corona Virus. CBD-Loaded exosomes hold the potential to provide a highly synergistic effect of anti-inflammatory properties and help in the recovery of infected lung cells. The techology, which is expected to be administered by inhalation, will be tested on a variety of lung infections. Exosomes are small particles created when stem cells are multiplied. Exosomes can act as “homing missiles” when the cell healing properties of the exosomes are combined with the anti-inflammatory properties of CBD. Exosomes also have an important role in cell-to-cell communication, which can be beneficial to additional treatments for CNS indications such as epilepsy and Alzheimer’s Disease.

Background

The world is suffering from a rapid rise in illness due to the fast growing spread of the COVID-19 pandemic. The lungs are the organ most affected by COVID-19, causing pneumonia that rapidly progresses to acute respiratory distress syndrome and can further result in respiratory failure, septic shock, multi-organ failure, and in the most severe cases death. Recent in-vivo and in-vitro studies have demonstrated that exosomes derived from mesenchymal stem cells (MSC) can promote regeneration and improve immune reaction processes in damaged tissues. Exosomes contain anti-inflammatory agents that can target inflamed organs. Prof. Offen and his team have already successfully loaded exosomes with various molecules. They have also succeeded in treating different tissue injuries in animal models, while significantly reducing inflammation and pathological impairment. To date, there have been hundreds of clinical studies using exosomes globally, demonstrating their therapeutic potential at different applications. Animal studies have also demonstrated CBD as effective in reducing lung inflammation. Based on these findings, InnoCan believes that its CLX therapy has the potential to treat the COVID-19 virus by combining CBD with exosomes, thereby creating therapeutic synergies. The suggested combination may have strong synergetic effects, thereby increasing the potential efficacy of planned treatments. Prof. Dani Offen, of the Sackler School of Medicine and Sagol School of Neuroscience  said, “I am pleased to work with the InnoCan team on this exciting CLX development project. We are facing a challenging time, and I believe our unique approach holds a promise to offer a treatment for COVID-19, pneumonia and perhaps for other lung inflammations as well.” Iris Bincovich, CEO of InnoCan’s CEO, also commented, “COVID-19 has quickly become one of the largest challenges in healthcare today. With the development of CLX, we are creating a new treatment, to join the global mission to combat the effects of COVID-19. We are determined to make a difference as quickly as possible to assist patients worldwide.” Keren Primor Cohen, CEO of Ramot at Tel Aviv University, summarized, “We hope that this collaboration with Innocan will assist in transforming Prof. Offen’s promising technology into a real treatment for the global threat of COVID-19”. Featured image: Prof. Daniel Offen (photo: Jonathan Blum)

Related posts

Hyperbaric Treatment More Effective than Medicines for Fibromyalgia Caused by Head Injury

24 March 2023

Promoting Women in Medicine

9 March 2023

#TAU_WOMEN_POWER

7 March 2023

Researchers Discover Mechanism that Facilitates Formation of Brain Metastases

27 February 2023

Light Pollution is Killing Desert Rodents

10 February 2023

Three Tel Aviv University Researchers Awarded the ERC Proof of Concept (PoC) grants

9 February 2023

Researchers Identify A New Genetic Risk Factor for Age-related Eye Disease

8 February 2023

People With Autism Experience Pain at a Higher Intensity

31 January 2023

Researchers Uncover New Factors Linked to Williams Syndrome

24 January 2023

Lessons in Tolerance and DNA Extraction in Tel Aviv University’s Medical Labs

18 January 2023

Medical Clowns – No Laughing Matter

18 January 2023

Tel Aviv University’s First MedTech Hackathon Sets a High Bar

15 January 2023

Researchers use Smartwatches to Measure Safety of COVID Vaccine

28 December 2022

Tel Aviv University Establishes Multidisciplinary Center for Research of Autoimmune Diseases

18 December 2022

Breakthrough in the Field of Controlled Drug Delivery

16 December 2022

Common Medications May Reduce Risk of Metastases after Colon and Rectal Cancer

9 December 2022

Victoria

Tok Corporate Centre, Level 1,
459 Toorak Road, Toorak VIC 3142
Phone: +61 3 9296 2065
Email: office@aftau.asn.au

New South Wales

Level 22, Westfield Tower 2, 101 Grafton Street, Bondi Junction NSW 2022
Phone: +61 418 465 556
Email: davidsolomon@aftau.org.au

Western Australia

P O Box 36, Claremont,
WA  6010
Phone: :+61 411 223 550
Email: clivedonner@thelinqgroup.com